ASCO trial sees 30% response in pediatric tumors on Ascentage combo
Ascentage Pharma (NASDAQ: AAPG) announced new clinical data from six trials presented at ASCO 2026, featuring three lead drug candidates: olverembatinib, lisaftoclax, and alrizomadlin. Highlights include a 30% objective response rate (ORR) and an 80% disease control rate (DCR) in heavily pretreated pediatric solid tumors using a combination of alrizomadlin and lisaftoclax, with a manageable safety profile. The company also reported promising results for olverembatinib in chronic myeloid leukemia (CML) and SDH-deficient tumors, with two global Phase 3 registrational trials currently enrolling patients.