Genmab reports Phase 3 trial shows major survival gains for ovarian cancer drug Rina‑S
Genmab A/S announced that its investigational antibody‑drug conjugate rinatabart sesutecan (Rina‑S) met its primary endpoint of progression‑free survival and the key secondary endpoint of overall survival in a global Phase 3 trial of platinum‑resistant ovarian cancer. In the intent‑to‑treat population of 584 patients, the drug cut the risk of disease progression or death by 71% and reduced the risk of death by 57% versus investigator‑chosen chemotherapy. The company said the safety profile was consistent with earlier data and will discuss the results with regulators worldwide.


