How Low Can PLSE Really Go In A Market Crash?
This article analyzes Pulse Biosciences (PLSE) stock's performance during past market crashes to assess its risk profile. It reveals that PLSE has averaged a -34% contraction during eight major market dislocations, significantly underperforming the S&P 500's -15% drop. The analysis details PLSE's drawdowns during specific events like the 2022 Fed Tightening Inflation Bear Market (-92%) and the 2025 US Tariff Shock (-29%), concluding that such steep contractions are a baseline expectation for the stock during market shocks.
How this was made

The 30-second read
Why it matters
The historical data suggests that PLSE is highly susceptible to market shocks, with potential for substantial declines, which should inform risk management strategies.
Market read
The biotech sector is sensitive to macroeconomic shocks, and PLSE's historical performance indicates high vulnerability during market downturns.
What to watch
Company-specific developments, such as new product approvals or partnerships, could offset sector-wide declines and influence PLSE's recovery trajectory.
Background
This article analyzes historical performance of PLSE during past market crashes to assess its risk profile, revealing significant average drawdowns.
Ticker impact
High relevance due to direct focus on Pulse Biosciences (PLSE) stock and its historical performance during market crashes.
Potential for a decline of approximately 30-40% in a severe market crash, aligning with historical average drawdowns.
Based on historical performance during past crashes, PLSE has shown considerable vulnerability. However, future declines depend on the nature of the market shock and company-specific factors, which are uncertain.
Market effects
The biotech sector may experience heightened volatility during market crashes, impacting PLSE and similar stocks.
US markets are likely to see increased declines, affecting biotech stocks like PLSE.
Limited; PLSE's performance is primarily influenced by US market conditions and sector-specific factors.
Counterpoint
PLSE's innovative therapies could lead to resilience and quicker recovery post-crash, making it a potential contrarian buy during downturns.
Key entities
- CompanyPulse Biosciences
A biotech company specializing in bioelectric medicine and cell-based therapies.


