$SYRE

Burrows Scott L sold $184K of SYRE

Burrows Scott L (Chief Financial Officer) sold 2,599 shares of Spyre Therapeutics, Inc. (SYRE) at $70.77 ($0.18M total) on 2026-06-01 under a Rule 10b5-1 trading plan.

Original reporting
SEC EDGAR · Burrows Scott L
Published Jun 4, 2026, 1:30 AM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Jun 4, 2026, 1:33 AM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
AlphAI market briefInsider activity
Primary signal
$SYRE
Neutral
medium confidence
Mentioned
$SYRE
Relevance
6/10
AlphAI data visualization · based on SEC EDGAR
Decision brief

The 30-second read

$SYRENeutralLow
01

Why it matters

The disclosure provides a datapoint on insider activity but does not introduce new company-specific fundamentals (no earnings, trial, deal, or regulatory action mentioned).

02

Market read

Traders may monitor for follow-on insider activity, but the 10b5-1 structure generally limits immediate trading signal strength.

03

What to watch

The filing does not disclose reasons for sale; traders should avoid over-interpreting 10b5-1 transactions as bearish fundamentals.

Relevance 6/10Novelty 3/10Timing: Filed June 3; sale executed June 1 (10b5-1 open-market).

Background

This is an SEC Form 4 insider transaction disclosure for Spyre Therapeutics (SYRE).

Company-level read

Ticker impact

$SYRENeutralMedium confidence
Context

Spyre Therapeutics CFO Burrows Scott L sold $183,931 of SYRE shares in an open-market transaction under a pre-arranged 10b5-1 plan.

Expected impact

Near-term impact likely muted; any reaction may be sentiment-driven rather than fundamental.

Evidence & confidence

The filing is a routine insider sale with stated 10b5-1 plan, which typically reduces interpretive weight versus unscheduled selling.

Market effects

Minimal—single-company insider transaction with no stated operational/regulatory catalyst.

None.

None.

Counterpoint

Because the sale is pre-arranged, it could be mechanically timed around liquidity needs without reflecting negative outlook.

Key entities

  • Spyre Therapeutics, Inc.

    SYRE, subject of the Form 4 insider sale by its CFO.

  • Burrows Scott L

    CFO who sold 2,599 SYRE shares at $70.7700 under a 10b5-1 plan.

Full insider trading history

This story covers one filing. See everything behind it: every insider buy and sell on record, 10b5-1 plans, late filings, and which officers and directors are trading.

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