$ELVN

Collins Helen Louise sold $219K of ELVN

Collins Helen Louise (CHIEF MEDICAL OFFICER) sold 5,000 shares of Enliven Therapeutics, Inc. (ELVN) at an average of $43.80 ($42.83–$44.74, $0.22M total) across 3 trades on 2026-06-17 under a Rule 10b5-1 trading plan.

Original reporting
SEC EDGAR · Collins Helen Louise
Published Jun 22, 2026, 9:11 PM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Jun 22, 2026, 9:13 PM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
AlphAI market briefInsider activity
Primary signal
$ELVN
Neutral
medium confidence
Mentioned
$ELVN
Relevance
3/10
AlphAI data visualization · based on SEC EDGAR
Decision brief

The 30-second read

$ELVNNeutralLow
01

Why it matters

The newest disclosed fact is the CMO’s open-market sale totaling $219,016.85 across three trades at ~$42.83–$44.74, with holdings after the sale of 25,000 shares.

02

Market read

This provides a transparent datapoint on insider selling, but it is not a fundamental catalyst by itself.

03

What to watch

Traders may over-weight insider sales; the key is whether there are concurrent fundamental catalysts (trial/regulatory/financing) not mentioned here.

Relevance 3/10Novelty 5/10Timing: today’s SEC Form 4 filing (filed 2026-06-22) referencing sales on 2026-06-17

Background

The article is an SEC Form 4 insider transaction disclosure for Enliven Therapeutics (ELVN).

Company-level read

Ticker impact

$ELVNNeutralMedium confidence
Context

Enliven Therapeutics’ chief medical officer Helen Louise Collins sold about $219K of ELVN shares via an open-market sale under a 10b5-1 plan.

Expected impact

Low likelihood of a sustained price move solely from this Form 4; any impact would be sentiment-driven and short-lived.

Evidence & confidence

The filing is a disclosed insider sale (S) with a pre-arranged 10b5-1 plan, and the transaction size is modest relative to typical large-cap trading flows.

Market effects

Minimal sector read-through; this is company-specific insider activity rather than clinical/regulatory or financing news.

None.

None.

Counterpoint

Because the sale is under a 10b5-1 plan, it may reflect liquidity/compensation mechanics rather than bearish fundamentals.

Key entities

  • Enliven Therapeutics, Inc.

    Subject of the Form 4 insider transaction disclosure (ELVN).

  • Collins Helen Louise

    Chief Medical Officer who sold 5,000 shares under a pre-arranged 10b5-1 plan.

Full insider trading history

This story covers one filing. See everything behind it: every insider buy and sell on record, 10b5-1 plans, late filings, and which officers and directors are trading.

Related articles

$ELVNMedAI 8/10

Guggenheim reiterates Enliven Therapeutics stock rating on FDA alignment

Guggenheim reiterated a Buy rating and $78 price target for Enliven Therapeutics (ELVN) after FDA alignment on its Phase 3 study design for relcobatinib. The stock is down 10.5% this week but up 169% YTD. Multiple analysts have initiated coverage with positive ratings and price targets ranging from $70 to $78. The Phase 3 trial will enroll 450 patients and is set to start by year-end 2026.

$ELVNMedAI 8/10

Enliven Therapeutics Announces FDA Alignment on ENABLE-2 Phase 3 Trial Design for Relcobatinib (ELVN-001) in Previously Treated Chronic Myeloid Leukemia

Enliven Therapeutics (ELVN) reached FDA agreement on the Phase 3 trial design for relcobatinib (ELVN-001) in treating chronic myeloid leukemia. The ENABLE-2 trial will compare relcobatinib to second-generation TKIs, with a target enrollment of 450 patients. The company plans to initiate the trial by year-end 2026.

$ELVNMed

Enliven Therapeutics stock initiated at Overweight by JPMorgan

JPMorgan initiated coverage on Enliven Therapeutics (ELVN) with an Overweight rating and a $75 price target, implying 64% upside. The stock has surged 198% year-to-date. Analysts highlight ELVN-001's potential in treating chronic-phase CML, with U.S. peak sales estimated at $5 billion. Recent reports from William Blair, Barclays, and Guggenheim also show positive outlooks.