$DFTX

Wiley Matthew T. sold $129K of DFTX

Wiley Matthew T. (Chief Commercial Officer) sold 2,867 shares of Definium Therapeutics, Inc. (DFTX) at $45.03 ($0.13M total) on 2026-06-25 under a Rule 10b5-1 trading plan.

Original reporting
SEC EDGAR · Wiley Matthew T.
Published Jun 26, 2026, 8:30 PM UTC
Analysis
alphai AI DeskAI-generated
Added to alphai Jun 26, 2026, 8:34 PM UTC. Informational, not investment advice.
How this was made
alphai summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
alphai market briefInsider activity
Primary signal
$DFTX
Neutral
high confidence
Mentioned
$DFTX
Relevance
3/10
alphai data visualization · based on SEC EDGAR
Decision brief

The 30-second read

$DFTXNeutralLow
01

Why it matters

The disclosure provides transparency on insider selling activity but does not introduce new company-specific fundamentals or events.

02

Market read

Traders may monitor for follow-on insider activity, but this specific transaction is unlikely to drive a material repricing without additional catalysts.

03

What to watch

The filing does not state any change in company guidance, trial status, or financing; traders should avoid extrapolating fundamentals from a planned sale.

Relevance 3/10Novelty 3/10Timing: Filed 2026-06-26 after-hours; reflects sale executed 2026-06-25.

Background

The article is an SEC Form 4 insider transaction disclosure for Definium Therapeutics, Inc.

Company-level read

Ticker impact

$DFTXNeutralHigh confidence
Context

Definium Therapeutics CCO Wiley Matthew T. sold 2,867 shares in an open-market transaction at $45.03 on 2026-06-25 under a 10b5-1 plan.

Expected impact

Low near-term impact; any effect is likely limited to sentiment/flow rather than a new catalyst.

Evidence & confidence

The filing is a Form 4 insider transaction with explicit 10b5-1 pre-arrangement, and it discloses no new operating, regulatory, or financial datapoint beyond the sale details.

Market effects

No sector read-across; single-company insider sale with no disclosed business change.

None indicated.

None indicated.

Counterpoint

Because the sale is under a 10b5-1 plan, it may be mechanically scheduled and not a signal of deteriorating outlook.

Key entities

  • Definium Therapeutics, Inc.

    Subject of the Form 4 insider transaction; CCO sold shares under a 10b5-1 plan.

  • Wiley Matthew T.

    Chief Commercial Officer who executed the open-market sale.

Related articles

$DFTXMed

Definium Therapeutics Q2 Earnings Call Highlights

Definium Therapeutics (NASDAQ:DFTX) reported Q2 results and discussed Phase II GAD data for DT120, saying efficacy was seen by week one and remained significant through week 12, with improvements on secondary endpoints and favorable tolerability. It said VOYAGE and PANORAMA were re-estimated to exceed 99% power. Net loss was $159M, including $86.2M non-cash warrant fair-value expense. The company raised about $758M net in June and had about $1.1B cash to fund operations into 2030.

$DFTXHighAI 9/10

Definium Therapeutics Reports Second Quarter 2026 Financial Results and Recent Highlights

Definium Therapeutics (NASDAQ: DFTX) reported Q2 2026 results and Phase 3 updates for DT120 ODT. It said Phase 3 Emerge in major depressive disorder met primary and key secondary endpoints, with placebo-adjusted MADRS improvements of 8.1 points at Week 6 and 7.3 at Week 12. Voyage and Panorama topline data are expected Aug 10 and Sept 2026. Cash, cash equivalents and investments were about $1.1B as of June 30, 2026, after a $805M gross public offering.

$DFTXHigh

Definium Therapeutics, Inc. (DFTX): Results of Operations and Financial Condition

Definium Therapeutics, Inc. (DFTX) filed an SEC Form 8-K — Results of Operations and Financial Condition. EX-99.1 2 dftx-ex99_1.htm EX-99.1 EX-99.1 Exhibit 99.1 Definium Therapeutics Reports Second Quarter 2026 Financial Results and Recent Highlights Announced positive topline results from Phase 3 Emerge study of DT120 ODT in major depressive disorder (MDD), demonstrating rapid, robu

$APGEMed

Biotech Gives SBIO Its Best Month Since 2023

In June, the ALPS Medical Breakthroughs ETF (SBIO) returned 18.7%, its best month since Dec 2023, according to VettaFi. Apogee Therapeutics (APGE) added 2.18 pts after AbbVie (ABBV) agreed to acquire it for about $10.9B ($135.11/share). Definium (DFTX) added 1.58 pts after a Phase 3 MDD readout; other movers included Oruka (ORKA).

$DFTXHighAI 9/10

Definium's Phase 3 LSD Depression Data Stuns the Tape as AbbVie Spends $10.9 Billion on Apogee

Definium Therapeutics (DTFX), formerly MindMed, reported positive topline Phase 3 Emerge results for DT120 in major depressive disorder. In 149 patients, the drug showed an 8.1-point placebo-adjusted MADRS improvement at week 6 (p<0.0001), with benefit from week 1 through week 12 and no serious adverse events or suicidality signal. Separately, AbbVie agreed to buy Apogee Therapeutics for $135.11/share (~$10.9B, 49.5% premium).