$CLDX

Celldex Therapeutics (CLDX) Reports Q2 Loss, Misses Revenue Estimates

Celldex Therapeutics (CLDX) reported Q2 adjusted EPS loss of $0.94 per share, better than the Zacks Consensus Estimate of a $1.04 loss. Revenue was $0.02 million, far below the consensus estimate, down from $0.73 million a year earlier. The article cites a Zacks Rank #2 (Buy) and upcoming consensus outlook of -$1.07 EPS on $1.86 million revenue for the next quarter.

Original reporting
Published Aug 6, 2026, 11:10 PM UTC
Analysis
alphai AI DeskAI-generated
Added to alphai Aug 7, 2026, 10:00 AM UTC. Informational, not investment advice.
How this was made
alphai summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
alphai market briefEarnings
Primary signal
$CLDX
Neutral
medium confidence
Mentioned
$CLDX
Relevance
6/10
alphai data visualization · based on finance.yahoo.com
Decision brief

The 30-second read

$CLDXNeutralMed
01

Why it matters

EPS beat (+9.62% surprise) but revenues missed massively (down to $0.02M and 98.75% below consensus). The next actionable driver is management’s earnings-call commentary and any subsequent changes to near-term and full-year consensus estimates.

02

Market read

Traders get a concrete earnings datapoint (EPS beat) alongside a major revenue miss, implying a two-sided setup where guidance and estimate revisions will determine whether the stock sustains gains.

03

What to watch

The article highlights estimate revisions and a Zacks Rank #2, but does not quantify guidance changes; the market may instead anchor on the magnitude of the revenue miss and cash runway concerns not discussed here.

Relevance 6/10Novelty 6/10Timing: after-hours/next-session reaction to the Q2 earnings release and earnings-call commentary

Background

The article summarizes Celldex’s Q2 adjusted results versus Zacks Consensus and discusses how estimate revisions may influence near-term stock movement.

Company-level read

Ticker impact

$CLDXNeutralMedium confidence
Context

Celldex reported Q2 adjusted EPS of -$0.94, beating the -$1.04 consensus, while revenue was $0.02M versus a $0.73M year-ago and far below estimates.

Expected impact

Likely choppy trading around the earnings call, with upside bias only if guidance and revenue trajectory improve.

Evidence & confidence

The article provides concrete EPS and revenue outcomes versus consensus, but does not include new guidance numbers; it flags that management commentary and estimate revisions will drive the stock’s immediate move.

Market effects

Reinforces that small-cap biopharma can see EPS beats without revenue traction, keeping investors focused on pipeline and near-term commercialization signals.

No specific regional spillover described.

No global macro or cross-border catalyst described.

Counterpoint

EPS can be less informative for early-stage biopharma if revenue is structurally low; traders may fade the EPS beat unless management provides credible revenue/pipeline milestones.

Key entities

  • Celldex Therapeutics

    Biopharmaceutical company reporting Q2 adjusted EPS and revenue versus consensus, with near-term outlook tied to earnings-call commentary and estimate revisions.

Related articles

$CLDXMed

Celldex Therapeutics, Inc. (CLDX): Results of Operations and Financial Condition

Celldex Therapeutics, Inc. (CLDX) filed an SEC Form 8-K — Results of Operations and Financial Condition. EX-99.1 2 exh_991.htm PRESS RELEASE EdgarFiling EXHIBIT 99.1 Celldex Reports Second Quarter Financial Results and Provides Corporate Update Barzolvolimab Phase 3 chronic spontaneous urticaria studies (EMBARQ-CSU 1 and 2) ongoing, topline data expected in Sept/Oct 2026; BLA submis

$AZNMed

Weekly Buzz: AZN, GSK JNJ Approvals; CUV Layoff, REGN, HALO, Samsun Deals, LLY, CLDX Data

Biotech weekly roundup highlights EU approval for AstraZeneca’s Etcamah plus CDK4/6 inhibitors in ESR1-mutant ER+/HER2- advanced breast cancer, and accelerated FDA approval for GSK’s Jideytro in ROS1+ NSCLC. J&J received FDA De Novo for OTTAVA and reported Phase 3 PFS/OS gains for Talvey combos. Other items include deals (RGEN-BioLife, RPRX royalty buy) and trial updates for LLY, CLDX, and others.

$CLDXMedAI 8/10

Celldex Treatment Fails To Relieve Chronic Itch, Abandons Prurigo Nodularis Study - Celldex Therapeutics

Celldex Therapeutics said its 24-week, double-blind, placebo-controlled prurigo nodularis trial of barzolvolimab (140 patients) failed to meet the primary 12-week itch improvement endpoint and key secondary lesion outcomes. Mast cell depletion via reduced tryptase occurred, but symptoms did not improve. Celldex also previously halted EoE development. CLDX shares were down 6.06% premarket at $33.50.

$CLDXHighAI 8/10

Celldex’s mAb fails to show benefit in Phase II prurigo nodularis trial

Celldex said its subcutaneous monoclonal antibody barzolvolimab failed in a Phase II randomized, double-blind, placebo-controlled trial in prurigo nodularis (NCT06366750). Patients did not achieve significant improvement on the WI-NRS at week 12 versus placebo, and key secondary endpoints also missed. Celldex is discontinuing the PN Phase II study; stock was expected to fall at the open.

$SMCIHighAI 8/10

After-Hours Stock Movers: SMCI, OKLO, XE, PEGA, CLDX, ALK By Investing.com

After-hours movers: Super Micro Computer (SMCI) rose ~20% on a bullish preliminary Q4 FY2026 update, with gross margins at 15% to 17% and new orders above $60B. Oklo (OKLO) and X-Energy (XE) gained on reports of a $200M federal program for nuclear power for AI data centers. Pegasystems (PEGA) fell on Q2 EPS and revenue misses. Celldex (CLDX) dropped after a Phase 2 trial failed endpoints. Alaska Air Group (ALK) slid on a weaker Q3 outlook.