BriaCell stock choppy on melanoma vaccine milestone

BriaCell Therapeutics (BCTX) develops targeted immunotherapies for cancer, focusing on 'off-the-shelf' cellular treatments. CEO Dr. Williams discussed their pipeline, including Bria-IMT in a Phase 3 trial for metastatic breast cancer and Bria-PROS+ for prostate cancer, which recently received FDA clearance. The company aims to overcome cost and scaling challenges of traditional therapies.

BriaCell Therapeutics reported positive ASCO 2026 data for Bria-IMT in heavily pretreated metastatic breast cancer. Phase 2 results cited by the company showed 55% survival beyond 1 year and 27% beyond 2 years with the Phase 3-selected regimen; TWiST and quality-of-life analyses from the ongoing Phase 3 Bria-ABC study indicated meaningful benefit with no unexpected safety signals.

BriaCell Therapeutics (Nasdaq: BCTX; TSX: BCT) said its independent Data Safety Monitoring Board reviewed safety data from its pivotal Phase 3 Bria-ABC trial of Bria-IMT plus an immune checkpoint inhibitor in metastatic breast cancer and raised no safety concerns, recommending continuation without modifications. The DSMB issued its sixth consecutive positive recommendation; the study is under FDA Fast Track.

Lockheed Martin delivered Germany's first F-35A Lightning II fighter jet, marking a milestone in Germany's modernization program. Germany plans to acquire 35 F-35As, with deliveries starting this year and full operational capability by 2029. The aircraft will replace aging Tornado jets and support NATO operations. The first eight jets will be used for U.S.-based pilot training, with German deliveries beginning in late 2027.

Alphabet's Google plans to invest €13 billion ($15.1 billion) in AI infrastructure in Finland, including three data centers and a 22-year nuclear power deal with Fortum. The investment aims to leverage Finland's cold climate and low-carbon energy for cost-efficient AI expansion, supporting products like Gemini and YouTube. Fortum's stock rose 15.5% on the news, while Alphabet's shares fell 2.3% due to concerns over rising capital spending.

Warner Music Group (WMG) partnered with AI music startup Suno to launch models allowing users to create music inspired by licensed recordings. This follows a 2025 settlement of a copyright lawsuit. WMG reported Q3 revenue of $5.44B, up 9% YoY. The deal could create new revenue streams but faces legal risks and artist opposition. Hedge fund sentiment has declined.