Eledon Advances Tegoprubart In Islet Cell And Kidney Transplant Programs

Eledon Pharmaceuticals, Inc. (ELDN) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Eledon Pharmaceuticals Reports Second Quarter 2026 Financial Results and Recent Business Highlights Successful End-of-Phase 2 meeting with FDA supports advancement of tegoprubart into a global Phase 3 kidney transplantation trial, on track to initiate in late 2026 Lo

NewcelX (Nasdaq: NCEL) said it completed a Type B Pre-IND meeting with the FDA for NCEL-101 in type 1 diabetes, with FDA feedback aligning on a regulatory path toward IND-enabling activities and a planned clinical trial. The trial would combine NCEL-101 with Eledon Pharmaceuticals’ (Nasdaq: ELDN) tegoprubart (anti-CD40L).

Eledon Pharmaceuticals (ELDN) reported updated investigator-initiated trial results for tegoprubart, an anti-CD40L antibody, in type 1 diabetes patients receiving allogeneic islet cell transplants at the University of Chicago. According to the company, all 12 patients achieved insulin independence, with mean most recent HbA1c ~5.4% and stable graft function over a median 8 months (max 22). No rejection or de novo donor-specific HLA antibodies were reported. Eledon said it will seek FDA regulator

Apple plans to launch AI features in China in December, supported by Alibaba. The iOS 27.3 update will introduce 18 services, including writing tools, translation, and visual intelligence. This follows a beta test starting November 4, as stated by Apple.

Merck and Moderna's personalized mRNA vaccine for melanoma reduced relapse risk by 42% in a phase 3 trial, with 82.2% of vaccinated patients relapse-free after 2 years. The vaccine targets neoantigens unique to each patient's tumor, but concerns include high costs and potential limitations compared to existing immunotherapies, according to SCIENCE.

Tesla unveiled its second-generation Roadster on October 15, 2026, with production delayed to 2028. The car features cold-gas thrusters, a 0-60 mph time under 1 second, and a top speed of 230 mph. No price or battery details were announced. The original Roadster, produced from 2008 to 2012, had an estimated 2,450 units built, with used prices ranging from $20,000 to $199,000.