$MAZE

Coloma Jason V sold $594K of MAZE

Coloma Jason V (Chief Executive Officer) sold 22,638 shares of Maze Therapeutics, Inc. (MAZE) at an average of $26.24 ($25.77–$27.12, $0.59M total) across 4 trades over 2026-09-02 to 2026-09-03.

Original reporting
SEC EDGAR · Coloma Jason V
Published Sep 4, 2026, 8:24 PM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Sep 4, 2026, 8:42 PM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
AlphAI market briefInsider activity
Primary signal
$MAZE
Bearish
medium confidence
Mentioned
$MAZE
Relevance
5/10
AlphAI data visualization · based on SEC EDGAR
Decision brief

The 30-second read

$MAZEBearishLow
01

Why it matters

The CEO's sale may prompt short-term traders to sell, but the modest amount limits broader impact.

02

Market read

Insider sell is a routine disclosure with modest trading relevance.

03

What to watch

Potential upcoming clinical data or financing events not disclosed.

Relevance 5/10Novelty 4/10Timing: filed Sep 4 2026

Background

Form 4 filings disclose insider transactions; investors monitor them for signals.

Company-level read

Ticker impact

$MAZEBearishMedium confidence
Context

CEO Jason V. Coloma sold 22,638 shares for $593,954.87, reducing his stake to 27,362 shares.

Expected impact

Potential modest dip in MAZE price over the next few days.

Evidence & confidence

Sale size is modest (~$0.6M) but involves the CEO; market may view it as a negative signal.

Market effects

Limited impact on biotech sector; similar insider sales are common.

No regional effect beyond the stock.

Not globally relevant.

Counterpoint

The sale could be routine liquidity need, not a lack of confidence.

Key entities

  • Maze Therapeutics, Inc.

    Biotech firm developing therapies for rare diseases.

  • Jason V. Coloma

    Chief Executive Officer of Maze Therapeutics.

Full insider trading history

This story covers one filing. See everything behind it: every insider buy and sell on record, 10b5-1 plans, late filings, and which officers and directors are trading.

Related articles

$MAZEHigh

Why is Maze Therapeutics stock climbing today?

Maze Therapeutics (MAZE) stock rose 2.9% in pre-market trading after CIBC initiated coverage with an Outperformer rating and a $50 price target. The company has 13 buy-equivalent ratings. Vertex Pharmaceuticals' (VRTX) positive kidney disease data also boosted MAZE, as both companies work on APOL1 inhibitors. The S&P 500, Dow, and Nasdaq showed little movement, indicating the rally was driven by company-specific news.

$VRTXMedAI 8/10

Twin Moves: VRTX Rises On Kidney Disease Trial Results, MAZE Rallies Harder

Vertex Pharmaceuticals (VRTX) shares rose 3% after reporting positive trial results for inaxaplin in APOL1-mediated kidney disease (AMKD). The drug reduced protein leakage in urine by 42.7% for albumin and 44.7% for total protein in patients with modest proteinuria. Rival Maze Therapeutics (MAZE) shares jumped 25% on the read-through. Truist called the data a validation of APOL1 inhibition, estimating a market of over 100,000 patients and potential blockbuster sales for Maze's MZE829.

$MAZEMed

Maze Therapeutics, Inc. (MAZE): Results of Operations and Financial Condition

Maze Therapeutics, Inc. (MAZE) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Maze Therapeutics Reports Second Quarter 2026 Financial Results and Recent Highlights Enrollment in Phase 2 HORIZON trial of MZE829 on track; data from all cohorts expected in late 2026 or early 2027 Phase 2 CIPheR trial of MZE782 in PKU initiated and enrollment ongo