Medicus Surges on New Data

Medicus Pharma (MDCX) submitted a Phase 2b/3 trial design for Teverelix to the FDA, aiming to reduce the patient count from 1,500 to 600. The trial focuses on prostate cancer patients with cardiovascular risk. The company seeks a strategic partner for the program, with clinical readiness expected by year-end. FDA approval is not guaranteed, and no licensing deal is assured.

Medicus Pharma (MDCX) will focus SkinJect development exclusively on Gorlin syndrome patients with multiple basal cell carcinoma lesions, per its portfolio strategy. The FDA's concerns and the company's engagement with the agency influenced this decision. The Gorlin program follows a completed Phase 2 study and an authorized Phase 2b study set for July 2026.

Medicus Pharma (MDCX) will focus its SkinJect asset development on Gorlin syndrome patients with multiple basal cell carcinoma lesions, abandoning other indications. The shift follows regulatory feedback and commercial assessments, aiming to resolve FDA concerns. The U.S. market for Gorlin syndrome treatments is estimated at $1.1 billion, with potential peak revenues of $383 million. MDCX shares fell 2.23% premarket on Monday.

Medicus Pharma (MDCX) reported progress in its SkinJect program, confirming a 200-microgram patch dose for further studies. The company is focusing on Gorlin syndrome and seeking a partner for nodular basal cell carcinoma. A potential partnership could bring $25,000+ in reimbursement. Additionally, MDCX is collaborating with Pfizer on a CD228-targeted antibody-drug conjugate for melanoma and solid tumors, receiving $2M in funding.

Medicus Pharma (MDCX) reported positive Phase 2 trial results for SkinJect in treating skin cancer, with all 90 patients completing treatment. The company plans to advance a 200-microgram dose in a registrational trial for Gorlin syndrome and seek a partner for broader use. The FDA cleared the SKNJCT-005 study, with potential peak US revenue estimated at $383 million.

Medicus Pharma (MDCX) is shifting its focus to CD228V, an antibody-drug conjugate for solid tumors, with initial trials targeting melanoma. The company is also refining strategies for SkinJect and Teverelix, prioritizing Gorlin syndrome and acute urinary retention. CEO Dr. Raza Bokhari stated the changes aim to enhance long-term growth. Shares rose 5.1% on Tuesday.