$TWST

Twist Bioscience Shares Soar 10.27% to New High, Extending a Remarkable 493% Yearlong Rally Fueled by AI

Twist Bioscience Corp. shares rose 10.27% to $174.78, extending a 493% yearlong rally. The surge follows a data-services agreement with Eli Lilly's AI-driven drug discovery platform, TuneLab. The company raised full-year revenue guidance to $456M-$457M and aims for adjusted EBITDA breakeven by Q4. Despite strong growth, Twist remains unprofitable with a negative EBIT margin of 31.5%.

Original reporting
Published Sep 24, 2026, 3:45 PM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Sep 24, 2026, 4:34 PM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
Twist Bioscience Shares Soar 10.27% to New High, Extending a Remarkable 493% Yearlong Rally Fueled by AI — source image
Decision brief

The 30-second read

$TWSTBullishMed
01

Why it matters

The new Eli Lilly data‑services deal and raised guidance could sustain momentum, but valuation and cash‑burn remain concerns.

02

Market read

The announcement fuels a notable intraday price surge and underscores AI's expanding role in biotech, making the stock a near‑term trading focus.

03

What to watch

Operating cash flow turning positive and low debt provide a cushion, but the company is still far from profitability.

Relevance 7/10Novelty 7/10Timing: today

Background

Twist Bioscience is a synthetic DNA company that has seen a 493% rally over the past year, driven by AI‑related news and partnership announcements.

Company-level read

Ticker impact

$TWSTBullishHigh confidence
Context

Twist Bioscience announced a new data‑services agreement with Eli Lilly and raised full‑year revenue guidance, driving a 10.27% price jump to $174.78.

Expected impact

Potential further short‑term upside if partnership execution is confirmed; watch for pull‑back on valuation concerns.

Evidence & confidence

New contract and guidance are primary catalysts; the stock already showed strong momentum.

Market effects

Highlights growing AI‑driven demand in synthetic biology, potentially benefitting peers in biotech and contract manufacturing.

Positive for US biotech sector; may attract investor interest in AI‑enabled life‑science firms.

Shows cross‑industry AI collaboration (pharma‑biotech), signaling broader trend of AI integration in drug discovery.

Counterpoint

Valuation remains stretched relative to fundamentals; the rally may be driven more by short‑squeeze dynamics than sustainable earnings.

Key entities

  • Twist Bioscience Corp.

    Synthetic DNA technology firm.

  • Eli Lilly

    Pharmaceutical company with AI‑driven drug discovery platform TuneLab.

Related articles

$CDNAMed

Biotech Stocks At 52-Week Highs - CDNA +13%, GRAL +15%, TWST +16%, ADPT, RVTY

Several biotech stocks hit 52-week highs on September 24, 2026. CareDx (CDNA) rose 13% to $63.09, Grail (GRAL) climbed 15% to $126.81, Adaptive Biotechnologies (ADPT) gained 6% to $29.58, Revvity (RVTY) increased 6% to $152.26, and Twist Bioscience (TWST) surged 16% to $185.22. Key catalysts included regulatory milestones, clinical trial results, and strategic acquisitions.

$TWSTMed

Twist Bioscience Stock Jumps As Lilly AI Deal Fuels Bullish Target Hike

Twist Bioscience (TWST) stock rose 16.21% after announcing a partnership with Eli Lilly's AI drug discovery platform, TuneLab. The company reported Q3 revenue of $118.4M, with a gross margin of 52% but a net loss of $35.1M. Leerink raised its price target to $160, citing the AI-driven opportunity. TWST is trading at a high valuation with a price-to-sales ratio over 25.

$TWSTMed

Twist Bioscience Stock Jumps As AI Deals Fuel Bullish Target Hike

Twist Bioscience (TWST) stock rose 8.35% on September 24, 2026, driven by its AI partnership with Eli Lilly's TuneLab platform. The company's stock has seen significant gains recently, trading at $171.74 from $139 over a few weeks. TWST reported quarterly revenue of $118.38M, with a net loss of $35.05M. Leerink raised its price target to $160, citing AI drug discovery opportunities.

$TWSTHigh

TWST Jumps As Twist Bioscience Lands Lilly AI Drug Discovery Deal

Twist Bioscience (TWST) stock rose 7.1% following a deal with Eli Lilly for AI-driven drug discovery. Analysts see strong short-term momentum, with price targets at $160 (Leerink) and $144 (UBS). The company has high revenue growth but remains unprofitable, with Q3 free cash flow at -$8.6M. Balance sheet is stable, with a current ratio of 2.7.