Johnson & Johnson's TREMFYA Shows Improvement In Axial Psoriatic Arthritis

Johnson & Johnson (JNJ) reported long-term data from the CARTITUDE-2 study, showing 50% of 20 patients with multiple myeloma remained progression-free for five years after a single CARVYKTI infusion. The five-year overall survival rate was 69.2%, with a median progression-free survival of 60.5 months. JNJ is advancing CARVYKTI's evaluation and its broader multiple myeloma portfolio. The stock closed at $270.68, up 0.56%.

Johnson & Johnson (JNJ) reported that its Tremfya treatment showed significant improvement in spinal pain and stiffness in a Phase 4 study for axial psoriatic arthritis. The study met primary and secondary endpoints, including MRI-confirmed inflammation reduction. Tremfya is already approved for inflammatory conditions, and the study's safety profile aligned with its established profile. Detailed results are pending presentation at a scientific congress.

Johnson & Johnson reported positive results from clinical trials for Tremfya and Carvykti. Tremfya met primary and secondary endpoints in a psoriatic arthritis study, showing improvement in disease activity scores. Carvykti demonstrated 50% five-year progression-free survival in multiple myeloma patients. JNJ shares were down 0.20% to $270.24 at the time of publication.

Johnson & Johnson (JNJ) extended its 64-year dividend growth streak with a 3.1% quarterly raise, supported by projected $21 billion in free cash flow. The company's oncology drugs, like CARVYKTI and TREMFYA, offset losses from Stelara biosimilars. JNJ's dividend yield is 1.94%, and shares are up 31.11% year-to-date. The company aims for a 65th consecutive hike in 2027, subject to free cash flow and litigation risks.

Johnson & Johnson (JNJ) reported positive Phase 4 STAR trial results for TREMFYA in treating axial psoriatic arthritis. The drug met primary and major secondary endpoints, showing improvements in disease activity, axial symptoms, and MRI-measured inflammation at Week 24. The safety profile was consistent with previous findings. Detailed results will be presented at a future scientific congress.

Johnson & Johnson (JNJ) reported that 50% of patients in a Phase 2 study of CARVYKTI® (ciltacabtagene autoleucel) for early-line relapsed/refractory multiple myeloma achieved five-year treatment-free remission. The study, presented at the International Myeloma Society Annual Meeting, showed a 69.2% five-year overall survival rate and 60.5-month median progression-free survival. The company suggests earlier treatment may increase long-term remission and disease control.