Shattuck Labs plans phase 2 trial for SL-325 in hidradenitis suppurativa
Shattuck Labs (STTK) plans a Phase 2 trial for SL-325 in hidradenitis suppurativa, enrolling 150 patients. The trial will evaluate two doses against placebo, with primary endpoints at Week 16. Data is expected in 2028. The company also appointed Shoba Ravichandran as SVP, Clinical Development, and confirmed its cash runway extends into 2029.
How this was made
The 30-second read
Why it matters
The Phase 2 initiation signals progress toward potential FDA filing, which could materially affect valuation.
Market read
New trial start is a catalyst for STTK and may influence peer valuations in the dermatology biotech space.
What to watch
Potential competition from other DR3/TL1A blockers and the need for additional funding beyond 2029.
Background
Shattuck Labs (STTK) is a clinical‑stage biotech developing DR3/TL1A pathway antibodies.
Ticker impact
Shattuck Labs announced a Phase 2 trial for SL-325 in hidradenitis suppurativa, a new clinical development for the company.
likely upward pressure as the market anticipates positive trial data
Biotech stocks typically rally on new trial initiations, especially when cash runway is sufficient through 2029.
Market effects
May lift other dermatology‑focused biotech peers as investors reassess pipeline value.
Limited to US biotech sector; no broader regional effect.
Modest global relevance, primarily affecting US‑listed biotech investors.
Counterpoint
If the trial fails to meet endpoints, the stock could face sharp downside.
Key entities
- ExecutiveShobha Ravichandran
Appointed Senior Vice President, Clinical Development.

