AbbVie (ABBV) Outgrew Humira’s Collapse. Is its Forward P/E Fair for What Comes Next?
AbbVie (ABBV) reported Q3 revenue of $16.99B, up 10.2%, despite a 35.9% drop in Humira sales to $756M. Growth was driven by Skyrizi ($5.505B, +24.4%) and Rinvoq ($2.525B, +24.5%). Adjusted EPS rose 22.9% to $3.65. The company acquired Apogee Therapeutics for $10.9B to bolster its immunology pipeline. Management guided full-year adjusted EPS to $13.87-$14.07.
How this was made

The 30-second read
Why it matters
The earnings beat and forward guidance suggest a positive re‑rating for AbbVie, while the sizable acquisition underscores a strategic bet on future immunology pipelines.
Market read
Strong earnings and forward guidance make ABBV a candidate for short‑term upside, with sector ripple effects in biotech.
What to watch
The $10.9B cash acquisition of Apogee adds execution risk and may dilute near‑term earnings if integration costs rise.
Background
AbbVie reported its quarterly results, highlighting a 35.9% drop in Humira sales but offset by strong growth in its newer immunology drugs Skyrizi and Rinvoq, plus a recent $10.9B acquisition of Apogee Therapeutics.
Ticker impact
Quarterly earnings released with revenue $16.99B (+10.2%) and adjusted EPS $3.65 (+22.9%); full-year adjusted EPS guidance $13.87‑$14.07.
potential upside as market prices in strong guidance and growth in immunology franchise
Revenue beat, double‑digit EPS growth and forward‑looking guidance indicate improved profitability and growth trajectory.
Market effects
Immunology and biotech peers may see renewed investor interest as AbbVie's successors to Humira demonstrate strong growth.
U.S. large‑cap pharma sector could receive a modest lift.
Limited to pharma/biotech investors; no broad macro effect.
Counterpoint
If the market has already priced in the guidance, the stock may face limited upside and could be vulnerable to execution risk on new acquisitions.
Key entities
- companyAbbVie
U.S. pharmaceutical company (ticker ABBV) reporting earnings and guidance.
- companyApogee Therapeutics
Biotech acquired by AbbVie for $10.9B.


