This Stock Is Up More than 560% This Year, but It Could Drop by 38%, According to Wall Street
Moderna's (MRNA) shares have surged over 560% this year due to clinical and regulatory progress, including approval of its flu vaccine and positive cancer vaccine trial results. However, analysts suggest a 38% downside from current levels, with an average price target of $121. The company's market cap is $77 billion, despite limited revenue and profitability.
How this was made

The 30-second read
Why it matters
The article combines fresh regulatory approvals with a valuation critique, offering a nuanced view of short‑term risk versus long‑term growth potential.
Market read
The news could trigger short‑term selling pressure on MRNA while reinforcing the broader mRNA sector narrative.
What to watch
Potential partnership opportunities and future oncology indications may not be fully priced in.
Background
Moderna's stock has surged over 560% YTD, prompting valuation debates among Wall Street analysts.
Ticker impact
Moderna received FDA approval for its flu vaccine mFLUSIVA and reported positive Phase 3 results for its personalized cancer vaccine, indicating significant clinical progress.
likely downside as market prices in overvaluation concerns
While the approvals are material, the article emphasizes that the stock is overvalued and recommends waiting for a dip.
Market effects
Strengthens the biotech sector's pipeline narrative, especially for mRNA platforms.
U.S. biotech stocks may see mixed reactions as valuation concerns persist.
Limited to investors tracking mRNA therapeutics and vaccine developers.
Counterpoint
Despite overvaluation concerns, the new approvals could unlock significant revenue streams, supporting a longer‑term upside.
Key entities
- CompanyModerna
Biotech firm developing mRNA vaccines and therapeutics.
- CompanyMerck
Partner in the personalized cancer vaccine trial.


