Vaxcyte EVP, COO Jim Wassil sells $1.56m in shares

Vaxcyte's EVP and COO Jim Wassil sold 18,000 shares for $1.56m at $86.74 each on Oct 5, 2026, and acquired 18,000 shares via option exercise. He now holds 145,435 shares. Vaxcyte's OPUS-1 trial succeeded, with analysts raising price targets to $125-$146. The stock is down to $71.38 but up 63% over a year.

Original reporting
Published Oct 11, 2026, 2:31 AM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Oct 11, 2026, 3:10 AM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
AlphAI market briefFinancial news
Primary signal
$PCVX
Bearish
high confidence
Mentioned
$PCVX
Relevance
5/10
AlphAI data visualization · based on investing.com
Decision brief

The 30-second read

$PCVXBearishLow
01

Why it matters

The insider transaction adds a fresh data point for traders assessing short‑term sentiment, but the broader catalyst remains the ongoing trial progress.

02

Market read

Primary relevance stems from the new Form 4 insider sale, offering a modest trading signal.

03

What to watch

The sale was executed under a pre‑arranged 10b5‑1 plan, which may reduce the informational value of the trade.

Relevance 5/10Novelty 5/10Timing: recent insider filing, within the past week

Background

Vaxcyte (NASDAQ:PCVX) is a biotech developing the VAX‑31 vaccine; recent analyst upgrades and trial updates have been highlighted.

Company-level read

Ticker impact

$PCVXBearishHigh confidence
Context

Executive EVP/COO Jim Wassil sold 18,000 shares for $1.56M under a 10b5‑1 plan and bought the same number of shares via options, a new Form 4 filing.

Expected impact

likely modest downward pressure as the market prices the insider sell

Evidence & confidence

Form 4 disclosures of executive sales often prompt short‑term selling pressure, especially when the sale size is notable relative to insider holdings.

Market effects

Limited; the sale is company‑specific and does not affect the broader biotech sector.

None; impact confined to Vaxcyte investors.

Low; no broader market implications.

Counterpoint

The buy side of the transaction (option exercise) may indicate confidence, offsetting the sell pressure.

Key entities

  • Jim Wassil

    Executive Vice President, Chief Scientific Officer and COO of Vaxcyte

Related articles

$PCVXHighAI 9/10

Vaxcyte Reports Third Quarter 2026 Financial Results and Provides Business Update

Vaxcyte, Inc. (PCVX) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Vaxcyte Reports Third Quarter 2026 Financial Results and Provides Business Update VAX-31 Adult Indication: Announced Positive Topline Data from OPUS-1 Pivotal Phase 3 Trial; VAX-31 Met All Prespecified Primary Endpoints, Was Well Tolerated and Demonstrated a Safety P

$PCVXHighAI 8/10

Vaxcyte’s vaccine candidate met every main goal in a trial of 4,047 adults. More trial results are expected in 2027.

Vaxcyte's VAX-31 vaccine met all primary endpoints in a Phase 3 trial of 4,047 adults, showing safety and efficacy. The company plans to report more trial results in 2027 and submit a BLA in 2028. VAX-31 is designed to prevent pneumococcal disease. Vaxcyte also announced progress in its VAX-A1 vaccine candidate for Group A Streptococcus.

$PCVXHighAI 9/10

Vaxcyte Reports Third Quarter 2026 Financial Results and Provides Business Update

Vaxcyte reported Q3 2026 results, highlighting positive topline data from the OPUS-1 Phase 3 trial of VAX-31, meeting all primary endpoints. The company expects results from OPUS-2 and OPUS-3 trials in early 2027, supporting a BLA submission in 2028. Vaxcyte also announced progress in its VAX-31 infant indication and VAX-A1 Phase 1 study. As of September 30, 2026, the company had $3.4 billion in cash and investments.