AbbVie Highlights Long-Term SKYRIZI, RINVOQ Data Findings At ACG 2026
AbbVie presented 22 abstracts at ACG 2026, highlighting long-term data for SKYRIZI and RINVOQ in treating IBD. Phase 3 AFFIRM trial showed SKYRIZI's efficacy in Crohn's disease, with 74.5% of patients with fistulizing Crohn's disease achieving no draining fistulas after five years. RINVOQ also showed sustained improvements in difficult-to-treat Crohn's disease. ABBV stock closed at $276.47, up 1.49%.
How this was made

The 30-second read
Why it matters
The data suggest durable efficacy across multiple IBD subpopulations, supporting broader label expansions and potentially boosting AbbVie's revenue outlook.
Market read
First public disclosure of significant Phase 3 and long-term data for two key IBD therapies, likely to influence AbbVie's stock and sector sentiment.
What to watch
Potential safety concerns, pricing pressures, and competition from biosimilars could limit the commercial upside of SKYRIZI and RINVOQ.
Background
AbbVie highlighted 22 abstracts at the American College of Gastroenterology meeting, focusing on new Phase 3 and long-term extension data for its IBD drugs SKYRIZI (risankizumab) and RINVOQ (upadacitinib).
Ticker impact
AbbVie presented new Phase 3 AFFIRM data and long-term extension results for SKYRIZI and RINVOQ at the ACG 2026 meeting.
likely upward pressure as the market prices in stronger efficacy data for SKYRIZI and RINVOQ
First disclosure of robust Phase 3 and long-term extension results for two key drugs; data support expanded indications and could drive sales growth.
Market effects
Strengthens the biotech sector's outlook on IBD therapeutics and may lift peers developing IL-23 or JAK inhibitors.
U.S. biotech stocks could see modest gains; European IBD drug makers may face heightened competition.
Adds confidence to global investors tracking advanced therapy pipelines for Crohn's disease and ulcerative colitis.
Counterpoint
If the data fail to translate into regulatory approvals or market uptake, the hype could fade and the stock may underperform.
Key entities
- companyAbbVie Inc.
Pharmaceutical company presenting IBD data.
- drugSKYRIZI
IL-23 inhibitor in Phase 3 AFFIRM trial.
- drugRINVOQ
JAK inhibitor with real-world evidence.

