GSK's Ris‑Rez shows 61pc response rate in early lung cancer study
GSK reported that its drug Ris-Rez showed a 61% response rate at 8mg/kg dose in a phase Ib study, higher than the 32% at 6mg/kg. The company plans to use the 8mg/kg dose in its ongoing phase III trial. GSK noted manageable side effects, with serious issues in 42% of higher-dose patients. The results will be presented at the ESMO 2026 congress. As of 0905 BST, GSK shares were up 0.16% at 1,865.50p.
How this was made

The 30-second read
Why it matters
The data could improve market perception of GSK's oncology franchise and affect upcoming Phase III trial expectations.
Market read
First report of significant efficacy data; likely to generate modest price movement.
What to watch
Long‑term survival benefit and Phase III design details remain unknown.
Background
GSK announced early Phase Ib results for its experimental lung‑cancer drug Ris‑Rez, with a higher dose showing a 61% response rate.
Ticker impact
Phase Ib data shows 61% response at 8 mg/kg versus 32% at 6 mg/kg, new trial result first reported.
modest upside as market prices in the improved response rate
First disclosure of statistically better efficacy at the higher dose, with manageable safety, is material for investors.
Market effects
strengthens the oncology pipeline outlook for large pharma
UK and European pharma stocks may see modest gains
potentially influences global biotech sentiment
Counterpoint
Some investors may view the side‑effect rates as a risk that could temper price gains.
Key entities
- companyGSK
FTSE 100‑listed pharmaceutical company
- drugRis‑Rez
Experimental treatment for extensive‑stage small cell lung cancer


