RCS - Intnl. Biotechnology - Portfolio company Silence acquired by Merck KGaA
Silence Therapeutics (SLN) will be acquired by Merck KGaA for $20 per share, a 130% premium. Silence is a UK biotech company developing RNA-based medicines. The deal is part of a broader trend of pharmaceutical acquisitions. International Biotechnology Trust (IBT) holds a 0.7% stake in Silence.
How this was made

The 30-second read
Why it matters
The acquisition of Silence Therapeutics by Merck KGaA provides a sizable premium, likely enhancing IBT's net asset value and share price.
Market read
The deal is a primary M&A disclosure that could lift IBT's share price and reflects broader biotech consolidation trends.
What to watch
Potential integration risks and the actual cash availability of Merck KGaA.
Background
IBT is a London-listed biotech investment trust that regularly reports on its portfolio holdings.
Market effects
Biotech M&A activity may boost sector sentiment as pharma firms seek growth through acquisitions.
European biotech and pharma markets could see increased investor interest.
The deal highlights continued consolidation in the global biotech space.
Counterpoint
If the acquisition faces regulatory delays, the expected NAV boost could be delayed.
Key entities
- CompanyInternational Biotechnology Trust PLC
London-listed investment trust focused on biotech.
- CompanySilence Therapeutics
UK-based clinical-stage biotech developing siRNA medicines.
- CompanyMerck KGaA
German pharmaceutical and life‑science company acquiring Silence.


