Amarin’s icosapent ethyl shows survival benefit in cancer trial

Amarin's Phase 3 EMT2 trial missed the primary PFS endpoint but showed a statistically significant OS benefit (HR 0.68; p=0.030) for VAZKEPA/VASCEPA. The company noted this as an exploratory oncology signal for a CVD drug, requiring further confirmation and regulatory dialogue.

Amarin's drug VASCEPA failed to meet its primary endpoint in a colorectal cancer trial but showed a 5-year survival rate of 62% vs. 45% with placebo. The study, sponsored by the University of Leeds, found improved overall survival but not progression-free survival. Amarin plans further evaluation, citing potential long-term value.

Amarin (AMRN) reported Q2 2026 results on an earnings call. Total net revenue was $42.2M, down 42% year over year, mainly due to a $25M upfront licensing payment in 2025. U.S. product revenue fell to $32.2M, while Europe product revenue rose to $5.4M. Operating loss narrowed to $12.0M and cash and investments were $314.6M.

Strong international demand growth and lower operating expenses supported improved profitability metrics as Amarin reaffirmed confidence in its global commercialization strategy. Key Investor Takeaways Amarin (NASDAQ:AMRN) reported strong international in-market demand growth, with partner network sales increasing 59% year over year despite lower reported revenue.

AMARIN CORP PLC\UK (AMRN) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Amarin Reports 2026 Second Quarter Financial Results Demonstrating Early Success of Fully Partnered International Commercial Strategy and Continued Leading U.S. Market Presence Q2 2026 Results Highlight Global Volume Growth, Lower Operating Expenses and Positive Cash

Amarin (NASDAQ: AMRN) reported Q2 2026 results for the quarter ended June 30, 2026. Total net revenue fell to $42.2 million from $72.7 million in Q2 2025, while operating expenses dropped 59% to $27.0 million. The company said in-market demand for VASCEPA/VAZKEPA rose 59% YoY across its partner network and U.S. IPE market share increased to 48%. It expects FY 2026 cash growth and continued international volume growth under its Recordati partnership.