$PFE

Pfizer raises 2026 forecasts as Eliquis, cancer drugs drive third-quarter results

Pfizer raised its 2023 profit and revenue forecasts due to strong demand for Eliquis and cancer drug Padcev. It now expects $62B-$64B in sales and $2.95-$3.05 EPS. CEO Albert Bourla cited strong Q3 performance and confidence in the pipeline. The company has invested heavily in acquisitions, including Seagen and Metsera. Pfizer reported Q3 adjusted profit of $0.87 per share, above estimates, with revenue of $16.58B. Eliquis sales rose 25% to $2.52B.

Original reporting
Published Nov 3, 2026, 3:28 PM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Nov 3, 2026, 4:18 PM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
Pfizer raises 2026 forecasts as Eliquis, cancer drugs drive third-quarter results — source image
Decision brief

The 30-second read

$PFEBullishHigh
01

Why it matters

The guidance raise and Q3 beat provide a near-term earnings floor, but the pipeline catalyst timing (mevrometostat now in Q1 2027) is a key swing factor for longer-duration valuation.

02

Market read

Traders can update 2026 earnings expectations immediately based on the new sales and EPS ranges, and adjust positioning around the delayed 2027 pipeline readout.

03

What to watch

The mevrometostat data delay to Q1 2027 could shift near-term expectations for pipeline-driven growth, and the CFO transition may affect how investors interpret future guidance-setting credibility.

Relevance 9/10Novelty 9/10Timing: guidance update and CFO appointment disclosed today

Background

Pfizer is integrating acquired oncology and obesity assets (Seagen, Metsera) while facing looming patent expirations and COVID-19 product declines.

Company-level read

Ticker impact

$PFEBullishHigh confidence
Context

Pfizer raised full-year sales to $62B-$64B and EPS to $2.95-$3.05 after Q3 beats driven by Eliquis and Padcev demand.

Expected impact

Likely upward bias as the market reprices higher 2026 earnings power, tempered by the delayed mevrometostat readout into Q1 2027.

Evidence & confidence

The article discloses new, company-specific forecast numbers plus a fresh catalyst timeline (mevrometostat now expected in Q1 2027) and an executive transition (new CFO effective Nov 1).

Market effects

Strength in Eliquis demand and Medicare negotiation dynamics may influence sentiment across large-cap pharma anticoagulants and pricing negotiations.

US large-cap pharma sentiment likely supported by raised 2026 outlook and Q3 beat.

Limited direct global spillover beyond multinational pharma earnings/guidance read-through.

Counterpoint

The raised forecast may be more dependent on Eliquis and acquired assets than on durable pipeline execution, leaving upside vulnerable to later patent and trial outcomes.

Key entities

  • Pfizer

    Raised 2026 sales and EPS forecasts on stronger Q3 results led by Eliquis and Padcev demand; appointed new CFO.

  • Eliquis

    Blood thinner co-marketed with Bristol Myers Squibb; sales rose 25% to $2.52B in Q3.

  • mevrometostat

    Late-stage experimental cancer drug; data now anticipated in Q1 2027 instead of year-end.

  • Cecile Guegan

    Appointed CFO effective Nov 1, succeeding Dave Denton.

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Pfizer's Revenue Barely Moved. Its Forecast Just Went Higher

Pfizer (PFE) reported Q3 revenue of $16.6B, slightly down YoY but above estimates. Adjusted EPS was $0.87, exceeding forecasts. COVID-19 vaccine and Paxlovid sales declined, but Eliquis and Padcev saw growth. Pfizer raised its 2023 revenue outlook to $62B-$64B and EPS to $2.95-$3.05. The company also appointed a new CFO.

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Pfizer (PFE) beat Q3 forecasts with adjusted EPS of $0.87 vs. $0.73 expected and revenue of $16.58B vs. $15.87B expected. The company raised its 2026 guidance, citing strong performance in products like Eliquis and Padcev. Pfizer also named Cecile Guegan as permanent CFO.