Cerenome Reports Third Quarter 2026 Financial Results and Business Highlights Featuring REYOBIQ ReSPECT- LM Data and CNSide Commercial and Reimbursement…

CERENOME, INC. (CNSY) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Cerenome Reports Third Quarter 2026 Financial Results and Business Highlights Featuring REYOBIQ ReSPECT- LM Data and CNSide Commercial and Reimbursement Progress HOUSTON, November 13, 2026 – Cerenome, Inc. (Nasdaq: CNSY) (“Cerenome” or the “Company”), a CNS oncology

Event · Earnings
Original reporting
Published Nov 13, 2026, 9:51 PM UTC
Analysis
AlphAI AI DeskAI-generated
Added to AlphAI Nov 13, 2026, 9:54 PM UTC. Informational, not investment advice.
How this was made
AlphAI summarizes source reporting and applies a structured AI analysis for relevance, timing, sentiment and ticker impact. Always verify material claims with the original publisher.
AlphAI market briefEarnings
Primary signal
$CNSY
Neutral
medium confidence
Mentioned
$CNSY
Relevance
8/10
AlphAI data visualization · based on SEC EDGAR 8-K
Decision brief

The 30-second read

$CNSYNeutralMed
01

Why it matters

The earnings release combines a loss with significant clinical progress, creating a mixed signal for traders.

02

Market read

First‑time disclosure of Q3 results and trial enrollment completion provides fresh data for pricing CNSY and peers.

03

What to watch

Potential reimbursement expansion with Aetna and other payers could improve future revenue visibility.

Relevance 8/10Novelty 8/10Timing: today
AlphAI · Earnings readCNSY · Q3 2026 · ended 2026-09-30

Cerenome reports Q3 2026 net loss of $(8,657) thousand, or $(1.14) per share, on total revenue of $722 thousand as CNSide diagnostic revenue begins

↓Weak quarter

Total revenue fell from $1,397 thousand to $722 thousand as grant revenue ended, and the Q3 net loss widened from $(4,423) thousand to $(8,657) thousand. SG&A rose from $3,443 thousand to $5,158 thousand. Cash, cash equivalents and investments were $4.9 million at September 30, 2026, and total stockholders' equity was $(923) thousand. The positives are the first CNSide diagnostic revenue, new payer agreements and the Phase 2 ReSPECT-GBM enrollment completion.

Revenue
$722K
CNSide diagnostic revenue, net
$722K
EPS · GAAP
$(1.14)

Key metrics

shortened, hover for the filing’s print
MetricValueq/qy/y
Q3 2026 Total revenueGAAP$722K––
Q3 2026 Grant revenueGAAPnil (printed as -)––
Q3 2026 Diagnostic revenue, netGAAP$722K––
Q3 2026 Cost of revenueGAAP$912K––
Q3 2026 Research and development expenseGAAP$2.11M––
Q3 2026 Selling, general and administrative expenseGAAP$5.16M––
Q3 2026 Total operating expensesGAAP$8.18M––
Q3 2026 Operating lossGAAP−$7.46M––
Q3 2026 Interest incomeGAAP$119K––
Q3 2026 Interest expenseGAAP−$14K––
Q3 2026 Financing expensesGAAP−$1.62M––
Q3 2026 Change in fair value of financial instrumentsGAAP$490K––
Q3 2026 Other expenseGAAP−$179K––
Q3 2026 Total other income (expense)GAAP−$1.20M––
Q3 2026 Net lossGAAP−$8.66M––
Q3 2026 Net loss per share, basic and dilutedGAAP$(1.14)––
Nine months 2026 Total revenueGAAP$2.16M––
Nine months 2026 Grant revenueGAAP$1.44M––
Nine months 2026 Diagnostic revenue, netGAAP$722K––
Nine months 2026 Cost of revenueGAAP$912K––
Nine months 2026 Research and development expenseGAAP$9.24M––
Nine months 2026 Selling, general and administrative expenseGAAP$15.64M––
Nine months 2026 Total operating expensesGAAP$25.79M––
Nine months 2026 Operating lossGAAP−$23.63M––
Nine months 2026 Total other income (expense)GAAP−$978K––
Nine months 2026 Net lossGAAP−$24.61M––
Nine months 2026 Net loss per share, basic and dilutedGAAP$(3.50)––
Nine months 2026 Net cash used in operating activitiesGAAP−$21.04M––
September 30, 2026 Total assetsGAAP$12.2M––
September 30, 2026 Total stockholders' (deficit) equityGAAP−$923K––
September 30, 2026 Cash, cash equivalents and investmentsother$4.9M––

Segments

SegmentRevenueq/qy/y
CNSide diagnostic revenue, netThe filing states that Cerenome recognized $0.7 million in net diagnostic revenue in the quarter after estimated payer adjustments and price concessions, and that it submitted billing claims for approximately $1.55 million in gross billings at list prices. The filing describes Q3 as the first quarter of CNSide diagnostic revenue.$722K––
Grant revenueThe filing prints Q3 2025 grant revenue of $1,397 thousand and nine-month 2026 grant revenue of $1,439 thousand. It gives no explanation for the change.nil (printed as -)––

Capital returns

  • No share repurchases or dividends are reported in the filing.
  • Proceeds from the Distribution Agreement were $3,337 thousand in the nine months ended September 30, 2026, with payments for commissions and offering costs of $(191) thousand.
  • The filing states that the Company raised $3.8M under the Equity Distribution Agreement subsequent to the end of the quarter.
  • Proceeds from the underwritten public offering were $15,000 thousand in the nine months ended September 30, 2026, against offering costs for sale of common stock of $(1,362) thousand.

What drove it

  • The filing states that Cerenome recognized net diagnostic revenue of $722 thousand after estimated payer adjustments and price concessions.
  • The filing states that the Aetna agreement, effective November 1, is the first national CNSide payer agreement to include both tumor cell enumeration and molecular profiling.
  • The filing states that the Company's aggregate contracted footprint now represents approximately 190 million covered lives.
  • The filing states that the CNSide CSF Molecular Profile tests were available to order beginning October 12.
  • The filing states that enrollment in the Phase 2 ReSPECT-GBM study in recurrent glioblastoma was completed in October.

Concerns

  • Total revenue of $722 thousand is below the $1,397 thousand printed for Q3 2025, and grant revenue of nil compares with $1,397 thousand a year earlier.
  • The Q3 net loss of $(8,657) thousand is larger than the $(4,423) thousand printed for Q3 2025. Nine-month net loss of $(24,609) thousand compares with $(16,673) thousand.
  • Selling, general and administrative expense rose to $5,158 thousand from $3,443 thousand in the same quarter of 2025. The filing does not explain the change.
  • Financing expenses of $(1,618) thousand were recorded in Q3 2026 and nine-month 2026 with no comparable amount in the prior-year quarter.
  • Total stockholders' equity was $(923) thousand at September 30, 2026, against $3,996 thousand at December 31, 2025.
  • Accounts payable and accrued expenses were $8,210 thousand at September 30, 2026, against $5,920 thousand at December 31, 2025.
  • Cash, cash equivalents and investments of $4.9 million compare with $8.6 million at June 30, 2026, as stated in the filing.

What to watch

  • Quarterly CNSide diagnostic revenue after the first quarter of recognition, including payer collections against the $1.55 million in gross billings at list prices.
  • The Medicare reimbursement timing the filing describes as on track for the first half of 2027, and the separate Novitas Solutions coverage determination.
  • Cash runway against the $4.9 million of cash, cash equivalents and investments and the up-to-$20 million senior secured facility with royalty-based repayments.
  • Operating expense trend, given SG&A of $5,158 thousand in Q3 2026 and the planned build-out of the field sales team.
  • Mid-2027 topline readouts from the ReSPECT-LM and ReSPECT-GBM trials and the planned End-of-Phase 2 meeting with the FDA after ReSPECT-GBM data.
  • The Q3 earnings conference call on Monday, November 16, 2026 at 8:30 a.m. Eastern Time.

Balance sheet and cash flow

  • The filing states that cash, cash equivalents and investments totaled $4.9 million as of September 30, 2026, compared with $8.6 million as of June 30, 2026.
  • Cash and cash equivalents on the balance sheet were $879 thousand at September 30, 2026, against $4,256 thousand at December 31, 2025. Investments were $3,992 thousand against $4,356 thousand.
  • Total liabilities were $13,123 thousand at September 30, 2026, against $12,329 thousand at December 31, 2025. Convertible note was $3,851 thousand at September 30, 2026, against nil at December 31, 2025.
  • Net cash used in operating activities was $(21,044) thousand in the nine months ended September 30, 2026, against $(14,518) thousand in the nine months ended September 30, 2025.
  • Purchases of property and equipment were $(1,368) thousand in the nine months ended September 30, 2026, against $(37) thousand a year earlier.
  • Net cash provided by financing activities was $14,330 thousand in the nine months ended September 30, 2026, against $27,508 thousand a year earlier.
  • The filing states that in September the Company closed a senior secured financing facility up to $20 million with royalty-based repayments.
  • Accounts receivable were $722 thousand and inventory was $235 thousand at September 30, 2026, against nil for both at December 31, 2025. Grant receivable was $1,761 thousand against $322 thousand.

Analysis

Cerenome reported third-quarter 2026 total revenue of $722 thousand, all of it net diagnostic revenue from CNSide. The filing prints no grant revenue for the quarter, against $1,397 thousand in Q3 2025, so reported revenue fell year over year even as the diagnostic line began. The company states that the $722 thousand is after estimated payer adjustments and price concessions, and that it submitted billing claims for approximately $1.55 million in gross billings at list prices. The nine-month figures show total revenue of $2,161 thousand against $3,846 thousand, with grant revenue of $1,439 thousand against $3,846 thousand. The filing does not print a prior-quarter revenue figure, so a sequential comparison is not available from this document.

Costs rose faster than revenue. Cost of revenue was $912 thousand, a line that was not reported in the prior-year quarter. Research and development fell to $2,107 thousand from $2,436 thousand, while SG&A rose to $5,158 thousand from $3,443 thousand. Total operating expenses were $8,177 thousand against $5,879 thousand, and the operating loss widened to $(7,455) thousand from $(4,482) thousand. Below the operating line, financing expenses of $(1,618) thousand and a $490 thousand gain from the change in fair value of financial instruments produced total other expense of $(1,202) thousand, compared with other income of $59 thousand a year earlier. The net loss was $(8,657) thousand, or $(1.14) per share, against $(4,423) thousand, or $(1.03) per share. The filing does not explain the SG&A increase, the R&D decline or the financing expense, so the reader should weigh these as reported figures without a stated cause.

The balance sheet and cash flow show a tighter position. Cash, cash equivalents and investments were $4.9 million at September 30, 2026, down from $8.6 million at June 30, 2026, according to the release text. Net cash used in operating activities was $(21,044) thousand in the nine months, against $(14,518) thousand a year earlier. Financing inflows of $14,330 thousand in the nine months included the $15,000 thousand underwritten public offering and a $3,000 thousand convertible note and royalty obligation. Total stockholders' equity moved to $(923) thousand from $3,996 thousand at year end, and the release states that a senior secured facility of up to $20 million with royalty-based repayments closed in September. The company also states that it raised $3.8M under its Equity Distribution Agreement after quarter end.

Operationally, the release emphasises payer and product progress: coverage agreements with Medical Mutual, Health Care Service Corporation, Blue Cross Blue Shield of Michigan, Florida Blue and Aetna, a footprint the company puts at approximately 190 million covered lives, and the launch of CNSide CSF Molecular Profile tests for orders beginning October 12. On the therapeutics side, enrollment was completed in the Phase 2 ReSPECT-GBM study in October, with topline data expected in mid-2027, and interim Phase 1 ReSPECT-LM multi-dose findings reported no dose-limiting toxicities in the first 10 patients. The filing provides no quantitative 2027 guidance, so there is no printed revenue, margin or expense target to test against. The 2027 outlook is limited to milestones: continued CNSide commercial rollout, dose escalation in the LM multi-dose study and the mid-2027 readouts.

For a reader, the key facts are the step-down in reported revenue against the prior-year quarter, the widening operating and net losses, the low cash balance relative to a $(21,044) thousand nine-month operating cash outflow, and the negative equity. The release gives the CNSide reimbursement timing as the first half of 2027 and states that the company is on track for it, but it does not quantify expected CNSide revenue.

Management, verbatim

Recognition of our first quarter of CNSide® diagnostic revenue and commercial payments beginning in October is a tremendous landmark

Marc H. Hedrick, M.D., President and Chief Executive Officer

Most recently, with Aetna coverage, it gives physicians an in-network option for both tumor cell enumeration and molecular profiling.

Marc H. Hedrick, M.D., President and Chief Executive Officer

Not in the filing

stated, not guessed
  • No prior-quarter (June 30, 2026) income statement figures are printed, so sequential changes are not available.
  • No year-over-year or sequential percentage changes are printed for any line, so yoy_change and qoq_change are null.
  • No gross margin figure is printed for the quarter or nine months.
  • No prior-year figures are printed for cost of revenue, diagnostic revenue, interest expense, financing expenses, change in fair value of financial instruments and other expense, because the filing shows dashes or no line for those periods. Entries shown as dash in the filing are left null or as nil.
  • No numerical guidance or outlook for revenue, gross margin, operating expenses or tax rate is provided in the filing. The 2027 outlook covers milestones only.
  • No previous-period outlook document was provided, so vs_prior_guidance is empty.
  • No non-GAAP measures, adjusted EBITDA or free cash flow are printed. Free cash flow is not computed.
  • No consensus estimates, analyst expectations or share price reaction are included in the filing.
  • The conference call transcript is not provided, so management commentary beyond the press release is not available.
  • Cash, cash equivalents and investments of $4.9 million are stated in the release text and are not reconciled to a table line in the balance sheet, which shows cash and cash equivalents of $879 thousand and investments of $3,992 thousand.
  • The amount of the senior secured facility actually drawn is not printed.
  • The amount and terms of the convertible note and royalty obligation beyond the $3,000 thousand proceeds line are not printed.
  • The filing does not state a reason for the SG&A increase, the R&D decrease or the financing expenses.

Written by an AI language model from the company’s SEC earnings filing (Form 8-K Item 2.02, or Form 6-K for a foreign private issuer). Every figure is checked against the filing text, and a metric the filing does not print, or whose value, prior period and change do not add up, is dropped from the metrics. The model can still misread a table, in the metrics or in the text, so check a number in the filing before you rely on it. Consensus estimates, price targets and share-price reactions are not shown because they are not in the filing. AI-generated research, not investment advice.

Background

Cerenome, a Nasdaq‑listed CNS oncology company, announced its Q3 2026 financials and updates on its REYOBIQ radiopharmaceutical programs.

Company-level read

Ticker impact

$CNSYNeutralMedium confidence
Context

Cerenome filed its Q3 2026 8‑K, reporting $0.7 M revenue, $8.7 M net loss and completion of enrollment in its Phase 2 ReSPECT‑GBM trial.

Expected impact

likely pressure as investors price in the loss and cash burn, offset by potential upside from upcoming trial data.

Evidence & confidence

Losses and cash depletion are bearish, but the trial progress may attract speculative buying ahead of mid‑2027 readouts.

Market effects

Highlights ongoing investment in CNS oncology diagnostics and radiopharmaceuticals, may spur interest in peer biotech stocks.

Limited to US biotech sector; no broader regional effect.

Modest, as trial data could influence global oncology research pipelines.

Counterpoint

Despite the loss, the cash runway and trial milestones could support a short‑term rally on speculative hopes.

Key entities

  • Cerenome, Inc.

    Nasdaq‑listed biotech focused on CNS diagnostics and radiopharmaceuticals.

  • REYOBIQ™

    Investigational radiotherapy for leptomeningeal metastases.

Every CNSY earnings report

This story covers one filing. The ticker page keeps them all: each quarter's reported metrics with year-over-year and sequential comparisons, segments, guidance, and how the numbers landed against the company's own prior outlook.

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