Summit Therapeutics partners with AstraZeneca and Daiichi Sankyo on Phase III ivonescimab/Datroway trial

Summit Therapeutics announced a clinical collaboration with AstraZeneca and Daiichi Sankyo to evaluate ivonescimab together with the ADC Datroway. The partners will start with a Phase III study in first‑line triple‑negative breast cancer and will share trial costs, with AstraZeneca or Daiichi sponsoring. The agreement was disclosed on 2 Oct 2026.

Summit shares rose 1.5% in pre‑market trading following the announcement. Barclays lifted Summit’s price target to $20, suggesting analysts see potential upside from the collaboration.

  • 1The collaboration will begin with a Phase III trial in first‑line triple‑negative breast cancer.
  • 2Each company will contribute its therapy and share trial costs, with AstraZeneca or Daiichi Sankyo sponsoring the study.
  • 3Summit ended the second quarter with $690.7 million in cash and short‑term investments.
  • 4Summit raised more than $68 million this quarter.
  • 5Barclays raised Summit’s price target to $20 from $18.
  • 6Summit shares were up 1.5% in pre‑market trading.

Sources