Novartis agrees Abogen RNA therapy licensing deal worth up to $7.8bn

Novartis agreed to license worldwide rights to Abogen Biosciences' investigational autoimmune therapy ABO2203 and secured options on further RNA-platform programs. The agreement is worth up to $7.8bn, including a $575m upfront payment and potential development, regulatory and commercial payments. Closing remains contingent on customary conditions and regulatory clearances.

The deal gives Novartis an mRNA-based autoimmune candidate and option rights to additional Abogen programs. Its financial exposure beyond the upfront payment depends on option exercises and the achievement of specified milestones.

  • 1Novartis will receive worldwide rights to ABO2203 and exclusive options for additional potential therapies using Abogen's RNA platform.
  • 2Abogen is set to receive an upfront payment of USD 575 million.
  • 3If every option is exercised and agreed conditions are met, Abogen could receive up to approximately USD 7.2 billion in milestone payments.
  • 4The transaction requires customary closing conditions, including regulatory clearances.
  • 5ABO2203 is an mRNA-encoded CD19xCD3 T-cell engager under development for autoimmune diseases.

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