Ardelyx presents real‑world evidence that XPHOZAH lowers serum phosphate in dialysis patients

Ardelyx reported data from a real‑world analysis of more than 1,400 adult dialysis patients who started XPHOZAH, either alone or with a single phosphate binder. Over a six‑month follow‑up, average serum phosphate fell by 0.80 to 1.55 mg/dL. Between 16% and 41% of patients achieved a level below 5.5 mg/dL, and 60%‑70% stayed on therapy through day 180.

The reductions demonstrate XPHOZAH’s effectiveness in routine clinical practice, which may support broader adoption among dialysis providers. Continued therapy rates of 60%‑70% suggest acceptable tolerability, influencing prescribing decisions.

  • 1The analysis included more than 1,400 adults on dialysis with hyperphosphatemia who initiated XPHOZAH.
  • 2Adjusted mean serum phosphate reductions at month six ranged from 0.80 mg/dL to 1.55 mg/dL.
  • 3The probability of reaching a serum phosphate level below 5.5 mg/dL was between 16% and 41% at six months.
  • 4Between 60% and 70% of patients remained on XPHOZAH therapy at day 180.

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