Castle Biosciences posts Q3 revenue up 24% and lifts full‑year guidance

Castle Biosciences reported third‑quarter 2026 revenue of $102.9 million, a 24% increase year over year, driven by a 47% jump in TissueCypher test volume. The company posted a net loss of $4.1 million and adjusted EBITDA of $12.7 million, while generating $19.7 million of operating cash. It raised its full‑year 2026 revenue outlook to $385‑$395 million, up from the prior $365‑$375 million range.

The company says the higher guidance reflects continued strong demand for its core dermatology tests, implying better earnings prospects for the remainder of 2026. Investors will see a larger revenue target and a modest improvement in profitability metrics.

  • 1Q3 2026 revenue was $102.9 million, up 24% from Q3 2025.
  • 2TissueCypher test report volume increased 47% year over year in Q3 2026.
  • 3Full‑year 2026 revenue guidance was raised to $385‑$395 million from $365‑$375 million.
  • 4Net loss for the quarter was $4.1 million, including $11.2 million of stock‑based compensation.
  • 5Adjusted EBITDA for Q3 2026 was $12.7 million, compared with $9.2 million a year earlier.
  • 6Net cash provided by operating activities was $19.7 million in the quarter.

Sources