Jazz Pharmaceuticals raises 2026 revenue outlook after Q3 earnings

Jazz Pharmaceuticals reported third-quarter 2026 revenue of $1.2B, up 10% year over year, and raised 2026 revenue guidance to $4.775B-$4.85B. The quarter included the launch of Ziihera for first-line HER2-positive gastroesophageal adenocarcinoma and completion of the Actio acquisition. Jazz also reported a GAAP net loss of $483.4M for the quarter.

The higher revenue range gives investors an updated framework for Jazz's 2026 sales outlook. The Ziihera launch and Actio transaction expand the company's commercial and rare-epilepsy pipeline exposure, while the reported loss highlights the earnings effect of acquisition-related and development costs.

  • 1Xywav net product sales rose 12% year over year to $483 million in 3Q26.
  • 2Ziihera generated $21 million in 3Q26 sales after receiving FDA approval on August 25, 2026.
  • 3Jazz completed its Actio acquisition in September 2026, adding ABS-1230 (JZP6979) to its rare-epilepsy portfolio.
  • 4The company generated $1.3 billion in cash from operations during the first nine months of 2026.
  • 5Jazz reported a GAAP net loss of $483.4M in Q3 2026.
  • The Actio purchase price of $820M appears in one earnings recap but is not confirmed in the company materials provided.
  • The materials report different EPS figures, including a $-3.88 figure and a $7.48 per-share loss, without consistently identifying the same accounting basis.

Sources