SEC Form DEFA14A filed by Eledon Pharmaceuticals Inc.

Eledon Pharmaceuticals (ELDN) submitted an IND application for Tegoprubart in islet cell transplants. Initial studies showed 12 patients achieved insulin independence. The company plans a Phase 3 kidney transplant trial in Q4 2026. ELDN stock closed at $2.99, up 2.34% in pre-market trading.

Eledon Pharmaceuticals, Inc. (ELDN) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Eledon Pharmaceuticals Reports Second Quarter 2026 Financial Results and Recent Business Highlights Successful End-of-Phase 2 meeting with FDA supports advancement of tegoprubart into a global Phase 3 kidney transplantation trial, on track to initiate in late 2026 Lo

NewcelX (Nasdaq: NCEL) said it completed a Type B Pre-IND meeting with the FDA for NCEL-101 in type 1 diabetes, with FDA feedback aligning on a regulatory path toward IND-enabling activities and a planned clinical trial. The trial would combine NCEL-101 with Eledon Pharmaceuticals’ (Nasdaq: ELDN) tegoprubart (anti-CD40L).

Eledon Pharmaceuticals (ELDN) reported updated investigator-initiated trial results for tegoprubart, an anti-CD40L antibody, in type 1 diabetes patients receiving allogeneic islet cell transplants at the University of Chicago. According to the company, all 12 patients achieved insulin independence, with mean most recent HbA1c ~5.4% and stable graft function over a median 8 months (max 22). No rejection or de novo donor-specific HLA antibodies were reported. Eledon said it will seek FDA regulator

Analysts made notable calls this week. D.A. Davidson upgraded Broadcom (AVGO) to Buy with a $400 price target, citing AI-related growth prospects. William Blair downgraded Moderna (MRNA) to Market Perform due to valuation concerns. Argus downgraded Abbott (ABT) to Hold after its reduced growth outlook. Jefferies upgraded Rivian (RIVN) to Buy, citing progress in margins and execution. GF Securities raised AMD's (AMD) price target to $720, expecting strong data center growth.

The US approved a $2.1B deal for Ukraine to buy 500 Patriot PAC-3 interceptors from Lockheed Martin, funded by European partners and Canada. Ukrainian President Zelenskyy welcomed the move, emphasizing its importance for air defense during winter. The deal aims to counter Russian missile threats, with delivery expedited due to urgent security needs.