US Midday Movers: Robinhood and Moderna Lead Gains as Hut 8 and Alibaba Slide

Anixa Biosciences, in partnership with the Cleveland Clinic, is developing a breast cancer vaccine that has shown positive early results in a clinical trial. Moderna and Merck's mRNA cancer vaccine, combined with an immunotherapy drug, succeeded in a late-stage trial for skin cancer. Doctors and researchers are concerned that vaccine misinformation could hinder the adoption of new cancer vaccines, citing the HPV vaccine as a cautionary tale. Some state lawmakers have also resisted HPV vaccine ma

Moderna (MRNA) shares rose 1.06% as its cancer vaccine, intismeran autogene, showed promising phase 3 results. The company collaborates with Merck (MRK) on the vaccine, which could target multiple cancer types. Analysts estimate potential revenue of $16.8B by 2035, though profits will be shared. Moderna's market cap is $57.4B, reflecting confidence in its pipeline, including the recently approved mFLUSIVA influenza vaccine.

Telix Pharmaceuticals (TLX) announced FDA approval for Pixclara, a PET imaging drug for glioma. Pixclara is the first FDA-approved FET-PET imaging drug in the U.S. and is indicated for adults and pediatric patients. The approval may expand U.S. access to FET-PET imaging and support diagnosis and treatment planning. TLX stock closed at $11.29 on Friday and is up 8.95% in pre-market trading.

USA Rare Earth (USAR) completed a $2.8B acquisition of Serra Verde, expecting $1.8B EBITDA by 2030. TMC (TMC) faces regulatory delays in seabed mining. Both companies aim to benefit from U.S. critical minerals sourcing.

The FDA approved Telix Pharmaceuticals' Pixclara, the first FDA-approved FET-PET imaging drug for glioma. It helps differentiate glioma progression from treatment-related changes. Telix aims to expand its precision medicine platform into brain cancer, with Pixclara targeting amino acid transporters in glioma tissue. The approval addresses a significant unmet need in brain cancer imaging.

The ASX 200 was flat at lunchtime on Monday. Telix Pharmaceuticals (TLX) shares rose 4% after the FDA approved its PET imaging drug for glioma brain cancer. Other movers: Cleanaway (CWY) +4%, FleetPartners (FPR) +10%, REA Group (REA) in focus after ACCC contract changes. Oil prices surged above $107 due to Middle East tensions and a likely Fed rate hike.