Argenx agrees to buy Unnatural Products for $550 million upfront, plus milestones, to add oral peptide drugs to its immunology pipeline

Argenx (ARGX) agreed to acquire Unnatural Products (UNP) for up to $1.15B, combining UNP's peptide discovery platform with Argenx's immunology expertise. The deal includes $550M upfront and $595M in milestones. Argenx shares rose 5% on Euronext and 4% on Nasdaq following the announcement. Argenx's Vyvgart franchise reported $4.534B in net sales for 2026's first nine months, up 58% year-over-year.

argenx (ARGX) will acquire Unnatural Products (UNP) for up to $1.15bn, including $550m upfront. The deal adds macrocyclic peptide capabilities to argenx's immunology portfolio. UNP's team will continue operations in Santa Cruz, California, post-acquisition. The transaction is expected to close by year-end.

Argenx acquires Unnatural Products (UNP) for $550M upfront, gaining oral peptide drug capabilities. UNP's macrocyclic peptides resist digestion, enabling oral administration. Argenx's Vyvgart had $4.5B sales in 2026, up 58.1%. The deal complements Argenx's antibody expertise and competes with big pharma in immunology. UNP could receive up to $595M in milestones.

argenx (ARGX) agreed to acquire Unnatural Products (UNP) for up to $1.15B, adding a peptide discovery engine. argenx already held a minority stake in UNP. The deal expands argenx's immunology capabilities. Latham & Watkins advised UNP on the transaction.

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argenx acquires Unnatural Products for up to $1.15B, including $550M upfront, to expand its drug development capabilities with macrocyclic peptide technology. The deal adds oral and long-acting medicine potential. Unnatural Products will continue operating from Santa Cruz.