Actuate Therapeutics Reports Promising Initial Clinical Responses in Pediatric Cancers from Phase 1 Trial of Elraglusib
Actuate Therapeutics, Inc. announced promising initial clinical responses in pediatric cancers from its Phase 1 trial of elraglusib, noting two Complete Metabolic Responses in Ewing sarcoma and one Complete Response in neuroblastoma among 40 patients. The company plans to advance elraglusib's clinical development in 2026, especially for Ewing sarcoma, following its Rare Pediatric Designations from the FDA. Clinical responses and disease control were observed in 15 patients, with particular efficacy when elraglusib was combined with cyclophosphamide and topotecan.