ALUMIS INC.
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H.C. Wainwright reiterated a Buy rating and $15.00 price target on Alumis Inc (ALMS) after positive LATITUDE Atlas trial results for zaso. The stock trades at $6.85, down from its 52-week high. Analysts view the data favorably but note mixed reactions due to recent Phase 2b trial failures for Envudeucitinib.
On September 9, 2026, significant insider trading activity was reported. Alumis Inc. (ALMS) director acquired $10.7M in shares, while NVIDIA (NVDA) director sold $235.6M. Greenwave (GWAV) CEO bought $8M in shares, and BELITE BIO (BLTE) executives sold $31.9M. Workday (WDAY) director sold $17.9M in shares. Dell (DELL) insiders sold $48.1M. Inhibrx (INBX) and Cytosorbents (CTSO) directors also made notable purchases.
Alumis (ALMS) stock rose 6.3% in pre-market trading after presenting long-term skin-clearance data for envudeucitinib at the Cantor Fitzgerald Global Healthcare Conference. Management highlighted potential partnerships and insider Srinivas Akkaraju bought 986,000 shares. The FDA application for envudeucitinib is expected in Q4 2026.
Over the past 7 days, AlphAI's AI scored 1 news story mentioning ALMS (ALUMIS INC.). Coverage has skewed bullish: 1 bullish, 0 neutral, and 0 bearish.
Recent ALMS coverage spans technology, financial news and market movers.
In the last 30 days, ALMS insiders filed 4 SEC Form 4 transactions — 2 purchases ($5.8M) and 2 sales ($1.0M). The most active reporter was AKKARAJU SRINIVAS with 4 filings.
Positive trial data may drive the stock higher despite recent declines.
Net buying by insider may support ALMS price.
Positive Phase 2 data and insider buying suggest near‑term upside, but mixed lupus trial outcome adds risk.
The insider sale may signal limited confidence and could exert slight downward pressure.
Significant insider purchase by a director suggests confidence in the company's prospects.
AlphAI scores every news story that mentions ALMS with an AI model for sentiment and relevance, and aggregates insider trades from ALUMIS INC.'s SEC EDGAR Form 4 filings. Figures refresh continuously.
H.C. Wainwright reiterated a Buy rating and $15.00 price target on Alumis Inc (ALMS) after positive LATITUDE Atlas trial results for zaso. The stock trades at $6.85, down from its 52-week high. Analysts view the data favorably but note mixed reactions due to recent Phase 2b trial failures for Envudeucitinib.
3 min readOn September 9, 2026, significant insider trading activity was reported. Alumis Inc. (ALMS) director acquired $10.7M in shares, while NVIDIA (NVDA) director sold $235.6M. Greenwave (GWAV) CEO bought $8M in shares, and BELITE BIO (BLTE) executives sold $31.9M. Workday (WDAY) director sold $17.9M in shares. Dell (DELL) insiders sold $48.1M. Inhibrx (INBX) and Cytosorbents (CTSO) directors also made notable purchases.
3 min readAlumis (ALMS) stock rose 6.3% in pre-market trading after presenting long-term skin-clearance data for envudeucitinib at the Cantor Fitzgerald Global Healthcare Conference. Management highlighted potential partnerships and insider Srinivas Akkaraju bought 986,000 shares. The FDA application for envudeucitinib is expected in Q4 2026.
2 min readAKKARAJU SRINIVAS sold 96,131 indirectly-held shares of ALUMIS INC. (ALMS) at $10.55 ($1.01M total) across 2 trades on 2026-09-08.
1 min readAKKARAJU SRINIVAS purchased 986,721 indirectly-held shares of ALUMIS INC. (ALMS) at an average of $10.87 ($10.63–$11.17, $10.73M total) across 4 trades over 2026-09-04 to 2026-09-08.
1 min readAlumis Inc. (ALMS) reported that its Phase 2b LUMUS trial of envudeucitinib in systemic lupus erythematosus did not meet primary or secondary endpoints in the overall population. However, a prespecified subgroup with high interferon gene signature showed numerically higher responses. The company plans to discuss Phase 3 trial design with regulators. Envudeucitinib was generally well tolerated.
3 min readAlumis Inc. (ALMS) shares dropped 57% after its Phase 2b lupus study missed primary goals, though a patient subgroup showed promising results. The company plans to discuss a late-stage trial with regulators. Wells Fargo and Baird lowered price targets but maintained positive ratings. ALMS is down 3% year-to-date.
2 min readAlumis (ALMS) reported its Phase IIb LUMUS trial for envudeucitinib in lupus failed to meet primary and secondary endpoints, causing shares to drop 50%. The trial involved 408 patients and measured disease activity improvement over 48 weeks.
2 min readAlumis stock fell 54.2% in pre-market trading after its Phase 2b LUMUS trial for envudeucitinib in systemic lupus erythematosus missed primary and secondary endpoints. A subgroup of patients showed positive responses, but the overall trial population was under-represented. The company plans to discuss a Phase 3 program with regulators. The Nasdaq, S&P 500, and Dow Jones also declined, exacerbating the sell-off.
2 min readAlumis Inc. (ALMS) reported that its Phase 2b LUMUS trial of envudeucitinib for systemic lupus erythematosus (SLE) did not meet primary and secondary endpoints in the overall population. However, a prespecified subgroup of patients with high interferon gene signature (IFNGS-high) showed robust responses. The company plans to discuss Phase 3 development with regulators. Envudeucitinib was well tolerated. Alumis remains on track to submit an NDA for envudeucitinib in moderate-to-severe plaque psor
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