$ASMB

ASSEMBLY BIOSCIENCES, INC.

Assembly Biosciences is a biotechnology company developing therapies for serious viral diseases. Its pipeline includes clinical-stage programs for recurrent genital herpes, hepatitis delta virus and hepatitis B, as well as an oral, broad-spectrum non-nucleoside polymerase inhibitor in regulatory filing-enabling studies for transplant-associated herpesviruses. Its research programs also seek new antiviral targets and compounds. The company’s candidates include helicase-primase inhibitors ABI-5366 and ABI-1179, HDV entry inhibitor ABI-6250, HBV capsid assembly modulator ABI-4334 and transplant-associated herpesvirus inhibitor ABI-7272. Assembly Biosciences earns collaboration-related payments, including upfront and option fees, and may receive milestones and royalties under its agreement with Gilead Sciences. Gilead exercised its option to license the herpes simplex virus inhibitor program in December 2025. Assembly Biosciences is headquartered in South San Francisco, California.

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Assembly Biosciences to Present Positive Phase 1a Safety, Tolerability and Target Engagement Data for ABI-6250 at AASLD The Liver Meeting® 2026

Assembly Biosciences (ASMB) will present Phase 1a data for ABI-6250 at The Liver Meeting 2026. The data shows safety, tolerability, and target engagement, with plans to advance to Phase 2 studies for chronic HDV infection and cholestatic liver diseases. ABI-6250 is an oral NTCP inhibitor. The company aims to initiate Phase 2 studies in Q4 2026 and Q1 2027.

Why is Assembly Biosciences stock surging today?

Assembly Biosciences (ASMB) stock rose 4.9% after hours. The company opted into a 40% share of U.S. profits for its herpes drug program with Gilead Sciences. ASMB could receive $280M in milestones and royalties. The move was driven by company-specific news, not broader market trends. ASMB's cash runway extends into 2029, with a $75M payment from Gilead expected in Q4 2026.

ASMB sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 2 news stories mentioning ASMB (ASSEMBLY BIOSCIENCES, INC.). Coverage has skewed bullish: 1 bullish, 1 neutral, and 0 bearish.

Recent ASMB coverage spans financial news, market movers and corporate actions.

What's driving ASMB

AlphAI scores every news story that mentions ASMB with an AI model for sentiment and relevance, and aggregates insider trades from ASSEMBLY BIOSCIENCES, INC.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $ASMB

Score
$ASMBMedAI 8/10

A once-daily oral drug for hepatitis D is being tested; the only approved treatment requires daily injections.

Assembly Biosciences (ASMB) began a Phase 2 trial for ABI-6250, an oral drug for chronic hepatitis D. The study will assess safety and efficacy in 80 participants, with initial data expected in Q4 2027. ABI-6250 is a once-daily oral alternative to the current injectable treatment. Gilead (GILD) has an option to license ABI-6250 if Phase 2 results are positive.

$ASMBMedAI 8/10

Assembly Biosciences to Present Positive Phase 1a Safety, Tolerability and Target Engagement Data for ABI-6250 at AASLD The Liver Meeting® 2026

Assembly Biosciences (ASMB) will present Phase 1a data for ABI-6250 at The Liver Meeting 2026. The data shows safety, tolerability, and target engagement, with plans to advance to Phase 2 studies for chronic HDV infection and cholestatic liver diseases. ABI-6250 is an oral NTCP inhibitor. The company aims to initiate Phase 2 studies in Q4 2026 and Q1 2027.

$ASMBHigh

Why is Assembly Biosciences stock surging today?

Assembly Biosciences (ASMB) stock rose 4.9% after hours. The company opted into a 40% share of U.S. profits for its herpes drug program with Gilead Sciences. ASMB could receive $280M in milestones and royalties. The move was driven by company-specific news, not broader market trends. ASMB's cash runway extends into 2029, with a $75M payment from Gilead expected in Q4 2026.

$ASMBMed

ASSEMBLY BIOSCIENCES, INC. (ASMB): Completion of Acquisition or Disposition of Assets

ASSEMBLY BIOSCIENCES, INC. (ASMB) filed an SEC Form 8-K — Completion of Acquisition or Disposition of Assets. Exhibit 99.1 Assembly Biosciences Reports Second Quarter 2026 Financial Results and Recent Updates – Expanded ABI-6250 clinical development into cholestatic liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) – – Completed $115 mil

$ASMBLow

Assembly Biosciences: Q1 Earnings Snapshot

Assembly Biosciences Inc. (ASMB) reported a first-quarter loss of $9.1 million, or 54 cents per share. The biotech company generated $8.2 million in revenue for the period. Despite the quarterly loss, Assembly Biosciences shares have more than doubled in value over the last 12 months, though they have seen a slight decrease of just over 8% since the beginning of the year.

$ASMBMed

Assembly Biosciences (ASMB) CMO awarded 26,000 RSUs vesting through 2030

Assembly Biosciences' Chief Medical Officer, Anuj Gaggar, was granted 26,000 Restricted Stock Units (RSUs) as part of his annual equity compensation. These RSUs will vest in four equal installments annually from March 29, 2027, through March 29, 2030, provided he remains with the company. This grant represents 65% of his annual equity award, with the remaining 35% contingent on stockholder approval of an increase in shares authorized under the company's 2018 stock incentive plan.

$ASMBLow

Assembly Biosciences (ASMB) boosts CEO bonus target in 2026 plan

Assembly Biosciences (ASMB) has adopted a new 2026 Corporate Bonus Plan, effective January 1, 2026, designed to motivate and reward employees with performance-based cash bonuses. The plan outlines varying target bonus opportunities, up to 75% of base salary for the CEO, and distinguishes between corporate and individual objectives. Notably, the Compensation Committee also increased CEO Jason A. Okazaki’s bonus target from 60% to 65% of his base salary for fiscal 2026.

$ASMBMed

Wall Street Zen Upgrades Assembly Biosciences (NASDAQ:ASMB) to Strong-Buy

Wall Street Zen has upgraded Assembly Biosciences (NASDAQ:ASMB) from a "buy" to a "strong-buy," aligning with an overall "Moderate Buy" consensus despite mixed analyst opinions. This upgrade follows a significant beat in quarterly EPS and revenue, though negative EPS is still forecasted for the current fiscal year. The company's stock shows a market cap of $439.41 million, and institutional investors have been actively trading its shares.

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