$CADL

Candel Therapeutics, Inc.

5
0
0
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$3.2M
Tak Paul Peter
100%
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Med

Candel Therapeutics Announces Publication of Phase 2a Trial Data that Demonstrated Prolonged Survival after Systemic Immune Reactivation by Aglatimagene Besadenovec plus Valacyclovir in Patients with Unresectable Stage III/IV NSCLC with an Inadequate Response to ICI

Candel Therapeutics (CADL) reported phase 2a trial results showing median overall survival of 24.5 months in advanced NSCLC patients with inadequate response to immune checkpoint inhibitors. The trial involved 46 patients treated with aglatimagene besadenovec plus valacyclovir. Results were published in the Journal for ImmunoTherapy of Cancer. The company is advancing a phase 3 trial (AURORA) for this treatment.

Candel Therapeutics Announces New Data Showing Sustained Immune Remodeling More Than Two Years After Aglatimagene Besadenovec Treatment in Localized Prostate Cancer at ASTRO 2026

Candel Therapeutics (CADL) presented data at ASTRO 2026 showing aglatimagene besadenovec significantly increased immune response in prostate cancer patients over two years. The phase 3 trial showed 80% of aglatimagene patients had negative biopsies vs. 63% of controls. The company plans to submit a BLA based on these results.

Candel Therapeutics stock jumps on BofA upgrade to buy

Candel Therapeutics (CADL) shares rose 9.3% premarket after BofA Securities upgraded the stock to Buy and raised the price target to $18.00 from $12.00, citing positive outlook for the biotech sector and key catalysts.

CADL sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 5 news stories mentioning CADL (Candel Therapeutics, Inc.). Coverage has skewed bullish: 5 bullish, 0 neutral, and 0 bearish.

Recent CADL coverage spans financial news, market movers and earnings.

In the last 30 days, CADL insiders filed 2 SEC Form 4 transactions — no purchases and 2 sales ($3.2M). The most active reporter was Tak Paul Peter, Chief Executive Officer, with 2 filings. 100% of those filings were made under pre-arranged Rule 10b5-1 plans.

What's driving CADL

AlphAI scores every news story that mentions CADL with an AI model for sentiment and relevance, and aggregates insider trades from Candel Therapeutics, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $CADL

Score
$CADLMedAI 9/10

Candel Therapeutics Announces Publication of Phase 2a Trial Data that Demonstrated Prolonged Survival after Systemic Immune Reactivation by Aglatimagene Besadenovec plus Valacyclovir in Patients with Unresectable Stage III/IV NSCLC with an Inadequate Response to ICI

Candel Therapeutics (CADL) reported phase 2a trial results showing median overall survival of 24.5 months in advanced NSCLC patients with inadequate response to immune checkpoint inhibitors. The trial involved 46 patients treated with aglatimagene besadenovec plus valacyclovir. Results were published in the Journal for ImmunoTherapy of Cancer. The company is advancing a phase 3 trial (AURORA) for this treatment.

$CADLMedAI 8/10

Candel Therapeutics Announces New Data Showing Sustained Immune Remodeling More Than Two Years After Aglatimagene Besadenovec Treatment in Localized Prostate Cancer at ASTRO 2026

Candel Therapeutics (CADL) presented data at ASTRO 2026 showing aglatimagene besadenovec significantly increased immune response in prostate cancer patients over two years. The phase 3 trial showed 80% of aglatimagene patients had negative biopsies vs. 63% of controls. The company plans to submit a BLA based on these results.

How Are Dow, S&P 500, Nasdaq Futures Reacting After The Fed Hiked Interest Rates?

U.S. stock futures rose overnight after the Federal Reserve's 25 basis point rate hike, with Dow, S&P 500, and Nasdaq futures up 0.62%, 0.56%, and 0.57% respectively. The Fed's target rate now ranges from 3.75% to 4.00%. SpaceX (SPCX) shares climbed over 5% on Morgan Stanley's positive rating, while Fluence Energy (FLNC) dropped 15% after cutting fiscal 2026 guidance. Snap (SNAP) gained 2% after unveiling new AI products.

$CADLLow

Candel Therapeutics, Inc. (CADL): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Candel Therapeutics, Inc. (CADL) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. Exhibit 99.1 Candel Therapeutics Appoints Martine Zimmermann, PharmD, to its Board of Directors • Regulatory and quality expertise strengthens Board as Candel advances toward planned Biologics License Application (BLA) submission and potential commercial readiness NEEDHAM, Mass.,

$NEOHighAI 8/10

Biotech Stocks At 52-Week Highs - NEO, BLSM, RVMD, ORMP, CADL

NeoGenomics (NEO), BlossomHill Therapeutics (BLSM), Revolution Medicines (RVMD), Oramed Pharmaceuticals (ORMP), and Candel Therapeutics (CADL) reached 52-week highs on August 27, 2026. NEO reported Q2 revenue growth of 11% and a profit turnaround. BLSM began trading on Nasdaq and received FDA Fast Track designation. RVMD's lead drug, Rasonque, was FDA-approved. ORMP's net income increased significantly. CADL reported a higher net loss but plans a BLA filing for its lead drug.

$CADLMed

Candel Therapeutics Reports Second Quarter 2026 Financial Results and Recent Corporate

Candel Therapeutics, Inc. (CADL) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Candel Therapeutics Reports Second Quarter 2026 Financial Results and Recent Corporate Highlights • Planning to submit a Biologics License Application (BLA) for aglatimagene besadenovec (aglatimagene) in localized, intermediate- to high-risk prostate cancer in Q4 202

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