$EWTX

Edgewise Therapeutics, Inc.

No enriched coverage for $EWTX in the last 7 days.

No SEC Form 4 filings for $EWTX in the last 30 days.

See all $EWTX insider activity →
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Edgewise Therapeutics Unveils the Differentiated Mechanism of Action (MoA) of its Cardiac Sarcomere Modulator EDG-7500

Edgewise Therapeutics (EWTX) announced preclinical data showing its cardiac sarcomere modulator EDG-7500 improves cardiac relaxation while preserving systolic function. The company will host a webcast to discuss these findings. EDG-7500 is being evaluated for hypertrophic cardiomyopathy (HCM) and a Phase 3 trial is expected to begin in Q4 2026. Early clinical observations align with preclinical data, and a peer-reviewed publication is set to release.

Edgewise Therapeutics options flow shows lopsided call activity

Edgewise Therapeutics (EWTX) saw significant options activity, with a 6,000-contract diagonal spread indicating a bullish stance. Traders rolled ITM Sep $45 calls to OTM Oct $50 calls, targeting an 8.4% rally. EWTX stock is up 197% over the past year, driven by a $2.65B business sale. Analysts have mixed views on its valuation and profitability.

Russell Alan J sold $258K of EWTX

Russell Alan J (Chief Scientific Officer) sold 5,901 shares of Edgewise Therapeutics, Inc. (EWTX) at an average of $43.73 ($43.68–$44.46, $0.26M total) across 3 trades on 2026-08-12.

EWTX sentiment & insider activity

Recent EWTX coverage spans insider activity, mergers & acquisitions and earnings.

What's driving EWTX

  • Positive Phase 2 safety data and a clear path to Phase 3 could lift sentiment and attract biotech investors.

    prnewswire.com · Sep 22, 2026

  • The cash influx de‑risks the balance sheet and could trigger a re‑rating, supporting upside to $50 targets.

    investing.com · Sep 18, 2026

  • The Form 4 shows insider selling, but it is not accompanied by new fundamentals, guidance, or regulatory/clinical catalysts.

    SEC EDGAR · Aug 14, 2026

  • The filing discloses an officer open-market sale under a non-10b5-1 plan, which can modestly affect near-term sentiment but not fundamentals.

    SEC EDGAR · Aug 14, 2026

  • The filing discloses a fresh insider sale by the company’s Chief Business Officer, which can modestly affect near-term sentiment but does not change fundamentals by itself.

    SEC EDGAR · Aug 14, 2026

AlphAI scores every news story that mentions EWTX with an AI model for sentiment and relevance, and aggregates insider trades from Edgewise Therapeutics, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $EWTX

Score
$EWTXMedAI 8/10

Edgewise Therapeutics Unveils the Differentiated Mechanism of Action (MoA) of its Cardiac Sarcomere Modulator EDG-7500

Edgewise Therapeutics (EWTX) announced preclinical data showing its cardiac sarcomere modulator EDG-7500 improves cardiac relaxation while preserving systolic function. The company will host a webcast to discuss these findings. EDG-7500 is being evaluated for hypertrophic cardiomyopathy (HCM) and a Phase 3 trial is expected to begin in Q4 2026. Early clinical observations align with preclinical data, and a peer-reviewed publication is set to release.

$EWTXHighAI 9/10

Edgewise Therapeutics options flow shows lopsided call activity

Edgewise Therapeutics (EWTX) saw significant options activity, with a 6,000-contract diagonal spread indicating a bullish stance. Traders rolled ITM Sep $45 calls to OTM Oct $50 calls, targeting an 8.4% rally. EWTX stock is up 197% over the past year, driven by a $2.65B business sale. Analysts have mixed views on its valuation and profitability.

$EWTXMedAI 8/10

Edgewise Therapeutics Reports Second Quarter 2026 Financial Results

Edgewise Therapeutics (Nasdaq: EWTX) reported Q2 2026 results and said its EDG-7500 12-week Phase 2 CIRRUS-HCM trial showed positive top-line data in obstructive and nonobstructive HCM, with Phase 3 planned for Q4 2026. In July 2026, it completed selling sevasemten and its muscular dystrophy business to Servier for $1.55B upfront plus up to $1.1B milestones. Q2 cash was about $460.7M; net loss was $57.3M.

Edgewise Therapeutics Reports Second Quarter 2026 Financial Results

Edgewise Therapeutics, Inc. (EWTX) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 News Release Edgewise Therapeutics Reports Second Quarter 2026 Financial Results – Announced positive top-line data from 12-week Phase 2 CIRRUS-HCM trial with EDG-7500 in obstructive and nonobstructive hypertrophic cardiomyopathy (HCM) – – Completed sale of sevasemte

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