$INKT

MiNK Therapeutics, Inc.

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Biotech MiNK targets up to 300,000 ARDS patients as Phase 2 starts

MiNK Therapeutics reported its Q4 and full-year 2025 financial results, highlighting a cash balance of $13.4 million and advancing its Phase 2 ARDS and GVHD programs. The company plans to initiate its Phase 2 ARDS trial in the first half of 2026, targeting 200,000-300,000 patients annually in the US and EU, with clinical readouts expected in the second half of 2026. MiNK is also benefiting from non-dilutive funding, including a $1.1 million collaboration with C-Further and grants for its GVHD program.

MiNK Therapeutics to begin phase 1 trial of iNKT cell therapy for GvHD

MiNK Therapeutics will initiate a Phase 1 clinical trial for its lead therapy, agenT-797, to evaluate its potential in reducing graft-versus-host disease (GvHD) and other complications in patients with high-risk leukemias and blood cancers. The therapy is an off-the-shelf allogeneic invariant natural killer T (iNKT) cell therapy that has previously shown safety and immune-modulating activity. This trial marks the company's expansion into transplantation medicine, aiming to suppress inflammatory immune responses while preserving anti-leukemia activity.