$PEPG

PepGen Inc.

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No SEC Form 4 filings for $PEPG in the last 30 days.

Buy Rating on PepGen: DM1 Program De-Risked by Stronger Underlying Biology and Upside from Higher-Dose Cohorts

H.C. Wainwright analyst Ananda Ghosh maintained a Buy rating on PepGen Inc. with a $20.00 price target. Ghosh believes PepGen's DM1 program is de-risked due to stronger underlying biology observed in treated patients, despite a modest average splicing correction skewed by an anomalous patient. The analyst anticipates significant upside from higher-dose cohorts, expecting materially higher splicing correction which could serve as a key value inflection point for the stock.

PepGen stock tumbles 44% on disappointing trial results

PepGen Ltd (NASDAQ:PEPG) shares dropped 44% after-hours following disappointing Phase 2 trial results for its myotonic dystrophy type 1 treatment, PGN-EDODM1. The drug showed an average splicing correction of 7.3% compared to placebo, with an outlier patient significantly impacting the overall mean. Despite the setback, the company plans to report data from a higher dose cohort in late 2026 and has sufficient funding into mid-2027.