Veppanu launch brings new option for advanced breast cancer
Rigel Pharmaceuticals said its Veppanu (vepdegestrant) is now available by prescription in the US for adults with ER+/HER2-, ESR1-mutated advanced or metastatic breast cancer after progression on at least one endocrine therapy. Rigel calls it the first FDA-approved PROTAC, with a 200 mg daily dose and $29,400 per 30-day supply. The company cites improved progression-free survival vs fulvestrant in a pivotal trial.




