$SLXN

Silexion Therapeutics Corp

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No SEC Form 4 filings for $SLXN in the last 30 days.

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Silexion Therapeutics Corp: Silexion Therapeutics Reports New Positive Preclinical Findings Demonstrating Multi-Mechanism Immune Sensitization by SIL204 in KRAS-Driven Cancers

Silexion Therapeutics (NASDAQ: SLXN) reported new preclinical results for its SIL204 siRNA in KRAS-mutant pancreatic and NSCLC cell lines. SIL204 increased FAS (CD95) expression and decreased HLA-G, supporting a multi-pathway immune-sensitization rationale for combining with anti-PD-(L)1 therapies. The company is advancing SIL204 in Phase 2/3 after starting a first clinical trial site at Tel Aviv Sourasky Medical Center in late July 2026.

Silexion Therapeutics Corp (SLXN): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Silexion Therapeutics Corp (SLXN) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. false 0002022416 00-0000000 0002022416 2026-07-31 2026-07-31 0002022416 us-gaap:CommonStockMember 2026-07-31 2026-07-31 0002022416 SLXN:WarrantsExercisableForOrdinarySharesMember 2026-07-31 2026-07-31 iso4217:USD xbrli:shares iso4217:USD xbrli:shares UNITED STATES SECURITIES AND

SLXN sentiment & insider activity

Over the past 7 days, alphai's AI scored 1 news story mentioning SLXN (Silexion Therapeutics Corp). Coverage has skewed bearish: 0 bullish, 0 neutral, and 1 bearish.

Recent SLXN coverage spans financial news, corporate actions and technology.

What's driving SLXN

  • The dilutive financing and warrant terms are the immediate driver of SLXN’s sharp selloff, with near-term overhang into the Aug. 13 close.

    rttnews.com · Aug 12, 2026

  • The update strengthens the mechanistic rationale for SIL204 as a multi-pathway immune sensitizer and supports continued Phase 2/3 combination development with anti-PD-(L)1.

    finanznachrichten.de · Aug 4, 2026

  • Board composition change may affect governance and committee dynamics, but the filing states no disagreement with company operations.

    SEC EDGAR 8-K · Jul 31, 2026

  • Trial initiation is a meaningful biotech catalyst, but near-term tradability depends on safety readouts and expansion milestones.

    jpost.com · Jul 30, 2026

  • Approvals increase the likelihood warrants can be exercised and expand authorized shares, which can raise dilution over time.

    SEC EDGAR 8-K · Jul 21, 2026

alphai scores every news story that mentions SLXN with an AI model for sentiment and relevance, and aggregates insider trades from Silexion Therapeutics Corp's SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $SLXN

Score

Silexion Therapeutics Corp: Silexion Therapeutics Reports New Positive Preclinical Findings Demonstrating Multi-Mechanism Immune Sensitization by SIL204 in KRAS-Driven Cancers

Silexion Therapeutics (NASDAQ: SLXN) reported new preclinical results for its SIL204 siRNA in KRAS-mutant pancreatic and NSCLC cell lines. SIL204 increased FAS (CD95) expression and decreased HLA-G, supporting a multi-pathway immune-sensitization rationale for combining with anti-PD-(L)1 therapies. The company is advancing SIL204 in Phase 2/3 after starting a first clinical trial site at Tel Aviv Sourasky Medical Center in late July 2026.

$SLXNLow

Silexion Therapeutics Corp (SLXN): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Silexion Therapeutics Corp (SLXN) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. false 0002022416 00-0000000 0002022416 2026-07-31 2026-07-31 0002022416 us-gaap:CommonStockMember 2026-07-31 2026-07-31 0002022416 SLXN:WarrantsExercisableForOrdinarySharesMember 2026-07-31 2026-07-31 iso4217:USD xbrli:shares iso4217:USD xbrli:shares UNITED STATES SECURITIES AND

$SLXNMed

Israel launches world-first trial for deadly pancreatic cancer treatment

Tel Aviv Sourasky Medical Center and Israeli biotech Silexion Therapeutics (Nasdaq: SLXN) announced a first-in-world clinical trial of SIL204, an siRNA therapy targeting KRAS mutations in pancreatic cancer. The study will enroll about 18 patients initially to assess safety, then expand, potentially to 166. SIL204 will be injected into tumors and combined with standard systemic treatment.

$SLXNMed

Silexion Therapeutics Corp (SLXN): Submission of Matters to a Vote of Security Holders

Silexion Therapeutics Corp (SLXN) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. false 12-31 0002022416 00-0000000 NASDAQ NASDAQ 0002022416 2026-07-21 2026-07-21 0002022416 slxn:OrdinarySharesParValue0135PerShareMember 2026-07-21 2026-07-21 0002022416 slxn:WarrantsExercisableForOrdinarySharesAtAnExercisePriceOf1552500PerShareMember 2026-07-21 2026-07-21 UNITE

$SLXNMedAI 8/10

Silexion Therapeutics Corp: Silexion Therapeutics Receives Approval from Germany's BfArM to Initiate Phase 2/3 Clinical Trial of SIL204 in Locally Advanced Pancreatic Cancer

Silexion Therapeutics said Germany’s BfArM approved it to start a Phase 2/3 trial of SIL204 in locally advanced pancreatic cancer, following a positive ethics opinion from the North Rhine Medical Association. The company also has Israel approval. Site activation is underway, with first patient dosing expected in the coming weeks.

$SLXNLow

Silexion Therapeutics (SLXN) CSO logs sale-to-cover share transaction

Shirvan Mitchell, CSO and CDO of Silexion Therapeutics (SLXN), reported selling 22,818 Ordinary Shares on March 26, 2026, at $1.36 per share. This transaction was a "sale-to-cover" to address tax liabilities from a fully vested restricted share unit grant received in February 2026. Following the sale, Mitchell directly holds 27,889 Ordinary Shares and an adjusted stock option for 478 Ordinary Shares.

$SLXNHigh

Pancreatic cancer drug SIL204 gets Israel approval for human trial

Silexion Therapeutics (NASDAQ: SLXN) has received approval from the Israeli Ministry of Health to begin a Phase 2/3 clinical trial for SIL204, its drug candidate for locally advanced pancreatic cancer. The drug targets KRAS mutations, which are present in over 90% of pancreatic cancers, and has shown strong preclinical anti-tumor activity. Silexion plans to initiate human trials in Q2 2026 and expects to file for additional regulatory approvals in Germany and the EU by early 2027.

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