$SNDX

Syndax Pharmaceuticals Inc

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Syndax (SNDX) Sales Nearly Doubled, So Why Did The Stock Fall?

Syndax Pharmaceuticals (NASDAQ:SNDX) reported Q2 revenue of about $115 million, nearly doubling year over year, with Revuforj at $55 million (+91% YoY) and Niktimvo at $60 million (+67% YoY). Despite the growth, shares fell 2.41%. Management cited patient-start variability and ongoing profitability constraints, while pending Q4 data and pipeline updates remain key.

Syndax (SNDX) Q2 2026 Earnings Call Transcript

Syndax (SNDX) discussed its Q2 2026 earnings call, focusing on menin inhibitor Revuforj and axatilimab-related pipeline. Revuforj net revenue was $55 million, up 12% QoQ, with about 1,500 prescriptions, up 15% QoQ. Niktimvo Q2 net revenue rose to $60 million, up 67% YoY. The company reiterated expectations for Revuforj peak US net revenue above $2 billion.

Syndax Pharmaceuticals Inc (SNDX): Results of Operations and Financial Condition

Syndax Pharmaceuticals Inc (SNDX) filed an SEC Form 8-K — Results of Operations and Financial Condition. EX-99.1 2 sndx-ex99_1.htm EX-99.1 EX-99.1 Exhibit 99.1 Syndax Reports Second Quarter 2026 Financial Results and Provides Business Update • Total revenue of $73 million in 2Q26, a 92% year-over-year increase – • Revuforj ® (revumenib) net revenue of $54.7 million in 2Q26, a 91% ye

SNDX sentiment & insider activity

Over the past 7 days, alphai's AI scored 2 news stories mentioning SNDX (Syndax Pharmaceuticals Inc). Coverage has skewed bullish: 1 bullish, 1 neutral, and 0 bearish.

Recent SNDX coverage spans market movers, earnings and technology.

What's driving SNDX

  • Near-doubled revenue did not translate into immediate confidence due to patient-start variability, distant profitability, and partner accounting that understates Niktimvo economics.

    insidermonkey.com · Aug 12, 2026

  • The call emphasizes accelerating commercial momentum for Revuforj and continued demand for Niktimvo, with additional upcoming clinical data catalysts for Revumenib and axatilimab.

    yahoo.com · Aug 12, 2026

  • Commercial momentum is strengthening (large YoY revenue growth and prescription growth), while near-term catalysts are tied to 4Q26 Phase 2 topline data for axatilimab.

    SEC EDGAR 8-K · Aug 4, 2026

  • The article expands Syndax’s clinical roadmap across myelofibrosis, IPF, and EGFR-mutant lung cancer, creating multiple upcoming decision points (trial starts and IND timing).

    yahoo.com · Jul 14, 2026

  • This is a routine insider sale disclosure, not a new operating or regulatory catalyst.

    SEC EDGAR · Jul 9, 2026

alphai scores every news story that mentions SNDX with an AI model for sentiment and relevance, and aggregates insider trades from Syndax Pharmaceuticals Inc's SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $SNDX

Score

Syndax (SNDX) Sales Nearly Doubled, So Why Did The Stock Fall?

Syndax Pharmaceuticals (NASDAQ:SNDX) reported Q2 revenue of about $115 million, nearly doubling year over year, with Revuforj at $55 million (+91% YoY) and Niktimvo at $60 million (+67% YoY). Despite the growth, shares fell 2.41%. Management cited patient-start variability and ongoing profitability constraints, while pending Q4 data and pipeline updates remain key.

$SNDXMedAI 8/10

Syndax (SNDX) Q2 2026 Earnings Call Transcript

Syndax (SNDX) discussed its Q2 2026 earnings call, focusing on menin inhibitor Revuforj and axatilimab-related pipeline. Revuforj net revenue was $55 million, up 12% QoQ, with about 1,500 prescriptions, up 15% QoQ. Niktimvo Q2 net revenue rose to $60 million, up 67% YoY. The company reiterated expectations for Revuforj peak US net revenue above $2 billion.

Syndax Pharmaceuticals Inc (SNDX): Results of Operations and Financial Condition

Syndax Pharmaceuticals Inc (SNDX) filed an SEC Form 8-K — Results of Operations and Financial Condition. EX-99.1 2 sndx-ex99_1.htm EX-99.1 EX-99.1 Exhibit 99.1 Syndax Reports Second Quarter 2026 Financial Results and Provides Business Update • Total revenue of $73 million in 2Q26, a 92% year-over-year increase – • Revuforj ® (revumenib) net revenue of $54.7 million in 2Q26, a 91% ye

$SNDXMed

Syndax Pharmaceuticals Maps Growth Beyond Revuforj With Lung Cancer, Myelofibrosis Push

Syndax Pharmaceuticals (SNDX) outlined plans to expand Revuforj (menin inhibition) into myelofibrosis, including a Q4 proof-of-principle phase 1/2 trial in about 30 patients. It also expects to file an IND for SNDX-62122 in 2027. Syndax and Incyte are advancing axatilimab (Niktimvo) in chronic GVHD and IPF, and introduced SNDX-4321 for EGFR-mutant NSCLC with an IND expected by year-end.

Syndax Showcases Revuforj® (revumenib) Clinical Activity in Multiple Acute Leukemia Subtypes and Settings at EHA 2026

Syndax Pharmaceuticals reported multiple Revuforj (revumenib) abstracts at EHA 2026. In ROAR (R/R NPM1m/KMT2Ar), interim ORR was 82% (9/11) with 64% (7/11) CR/CRh. In SNDX-5613-0708 (newly diagnosed NPM1m/KMT2Ar), CRc was 97% (34/35) and MRD negativity 86% (25/29). Post-HSCT AUGMENT-101 analysis showed 12-month OS 95%. In SAVE (R/R AML), ORR was 88% (37/42) and MRD negativity 68% (25/37).

$SNDXMed

Syndax Pharmaceuticals Inc (SNDX): Entry into a Material Definitive Agreement

Syndax Pharmaceuticals Inc (SNDX) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. EX-4.1 2 d105044dex41.htm EX-4.1 EX-4.1 Exhibit 4.1 Execution Version SYNDAX PHARMACEUTICALS, INC. AND U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of June 10, 2026 2.25% Convertible Senior Notes due 2031 TABLE OF CONTENTS P AGE ARTICLE 1 DEFINITIO

$SNDXLow

Syndax Pharmaceuticals Inc (SNDX): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Syndax Pharmaceuticals Inc (SNDX) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. EX-10.1 2 sndx-ex10_1.htm EX-10.1 EX-10.1 Exhibit 10.1 SYNDAX PHARMACEUTICALS, Inc. 2026 Equity Incentive Plan Adopted by the Board of Directors: April 30 , 2026 Approved by the Stockholders: June 10 , 2026 1. General. (a) Successor to and Continuation of Prior Plan . The Plan is

$SNDXMedAI 9/10

Syndax Announces Private Placement of $250.0 Million of Convertible Senior Notes

Syndax Pharmaceuticals (NASDAQ: SNDX) said it entered private subscription agreements to issue $250.0 million of 2.25% Convertible Senior Notes due 2031, with an expected June 10, 2026 closing. Net proceeds are estimated at about $243 million for general corporate purposes. Notes pay semiannual interest, mature June 15, 2031, and have an initial conversion price of ~$24.76/share.

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