$STOK

Stoke Therapeutics, Inc. (STOK) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers (b) On September 22, 2026, Edward M. Kaye, M.D. notified the Board of Directors (the “Board”) of Stoke Therapeutics, Inc. (t

Stoke Therapeutics (STOK) appointed Bo Cumbo to its board, replacing Edward Kaye, who retired. Cumbo has extensive biopharma experience. Stoke is developing zorevunersen for Dravet syndrome, with potential FDA approval in 2028. It partners with Biogen (BIIB) for global commercialization, retaining U.S., Canada, and Mexico rights.

Stoke Therapeutics (STOK) presented at the Cantor Fitzgerald conference, highlighting progress in its Phase III EMPEROR trial for Dravet syndrome, which completed enrollment ahead of schedule with 162 patients. The company expects top-line data in Q3 2027 and plans a rolling NDA submission in H1 2027. Stoke reported $400M in pro forma cash as of June 30, 2024, providing a runway through early 2028. Open-label extension data show a 75% sustained seizure reduction over four years. The stock traded

Stoke Therapeutics (STOK) announced key milestones, including a phase III readout for Dravet syndrome within 12 months and progress in ADOA trials. Zorevunersen showed sustained 75% seizure reduction and functional gains, with long-term efficacy supported by OLE data. The EMPEROR study is well-powered, and the company's commercial strategy leverages robust clinical evidence.

Stoke Therapeutics and Biogen presented four-year data on zorevunersen, showing sustained seizure reductions and cognitive improvements in Dravet syndrome patients. The results, from Phase I/IIa studies and extensions, were shared at the 16th European Epilepsy Congress.

Stoke Therapeutics and Biogen presented long-term data at the 16th European Epilepsy Congress, showing zorevunersen's potential in treating Dravet syndrome. The Phase 1/2a and OLE studies demonstrated durable seizure reductions, cognitive and behavioral improvements, and quality of life enhancements. The Phase 3 EMPEROR study data is expected in Q3 2027, aiming to complete the U.S. NDA submission. Zorevunersen was generally well tolerated, with some patients treated for over 5 years. Dravet synd

Stoke Therapeutics (STOK) and Biogen (BIIB) presented 4-year data from Phase 1/2a studies of zorevunersen, an investigational treatment for Dravet syndrome, at the 16th European Epilepsy Congress. The data showed sustained improvements in cognition, behavior, and seizure reduction, with a generally well-tolerated safety profile. The Phase 3 EMPEROR study is ongoing, with results expected in Q3 2027.

Stoke Therapeutics (STOK) shares rose 1.4% in pre-market trading after JPMorgan initiated coverage with an Overweight rating and $40 price target. The company has 14 buy ratings, with no holds or sells, and recently completed patient enrollment in its Phase 3 EMPEROR study. STOK is trading at $31.85, 21% below its 52-week high.

Ticho Barry (CHIEF MEDICAL OFFICER) sold 4,767 shares of Stoke Therapeutics, Inc. (STOK) at an average of $32.03 ($32.01–$32.47, $0.15M total) across 2 trades on 2026-08-18.

Kaye Edward M. MD sold 12,567 shares of Stoke Therapeutics, Inc. (STOK) at an average of $32.03 ($32.01–$32.47, $0.40M total) across 2 trades on 2026-08-18.