Wave Life Sciences Ltd.: Wave Life Sciences Initiates Phase 2a Combination Trial of WVE-007 (GalNAc-siRNA) with Tirzepatide for Obesity
Wave Life Sciences (WVE) initiated a Phase 2a trial for WVE-007, its investigational GalNAc-siRNA, in combination with tirzepatide for obesity treatment. The trial aims to evaluate the combination therapy's efficacy in adults with obesity and type 2 diabetes. Wave also plans to initiate a maintenance trial for WVE-007 in the second half of 2026. Preclinical data suggest WVE-007 could enhance fat loss and preserve muscle when combined with GLP-1 therapies.


