$XFOR

X4 Pharmaceuticals, Inc

X4 Pharmaceuticals is a biopharmaceutical company developing and commercializing therapeutics for rare hematology diseases. Its primary asset is mavorixafor, an oral small molecule that selectively antagonizes the CXCR4 receptor. X4’s commercially approved product, XOLREMDI, is an oral, once-daily treatment for patients aged 12 years and older with WHIM syndrome, approved in the United States to increase circulating mature neutrophils and lymphocytes. Mavorixafor is also being studied in the Phase 3 4WARD trial for chronic neutropenia. X4 makes money through products it develops and commercializes itself or with partners. It provides U.S. access to XOLREMDI through a specialty pharmacy and works with international partners on commercialization. Norgine holds licensed commercialization rights in Europe, Australia and New Zealand, while taiba rare has distribution and commercialization rights in select Middle East and North African countries. X4 is headquartered in Boston, Massachusetts.

3
1
0
$12K
$34K
Craig Adam R
0%
See all $XFOR insider activity →
Med

X4 Pharmaceuticals Targets 2028 Phase III Data for Mavorixafor in Chronic Neutropenia

X4 Pharmaceuticals (XFOR) reported blinded data from its 4WARD study, showing promising results for mavorixafor in treating chronic neutropenia. The company plans to initiate a Phase II study (4STEPS) in 2027 to evaluate G-CSF reduction. X4 estimates a 15,000-patient U.S. market opportunity, with potential expansion to 30,000 patients. Clinicians highlighted the high disease burden and need for new treatments.

Virtual Investor Day October 29, 2026 Nasdaq: XFOR

X4 Pharmaceuticals, Inc (XFOR) filed an SEC Form 8-K — Other Events. Virtual Investor Day October 29, 2026 Nasdaq: XFOR Exhibit 99.1 2 This presentation, including any printed or electronic copy of these slides, the talks given by the presenters, the information communicated during any delivery of the presentation and any question-and-answer sessi

XFOR sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 4 news stories mentioning XFOR (X4 Pharmaceuticals, Inc). Coverage has skewed bullish: 3 bullish, 1 neutral, and 0 bearish.

Recent XFOR coverage spans insider activity, corporate actions and financial news.

In the last 30 days, XFOR insiders filed 2 SEC Form 4 transactions — 1 purchase ($12K) and 1 sale ($34K). The most active reporter was Craig Adam R, Executive Chairman, with 1 filing.

What's driving XFOR

AlphAI scores every news story that mentions XFOR with an AI model for sentiment and relevance, and aggregates insider trades from X4 Pharmaceuticals, Inc's SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $XFOR

Score

X4 Pharmaceuticals Targets 2028 Phase III Data for Mavorixafor in Chronic Neutropenia

X4 Pharmaceuticals (XFOR) reported blinded data from its 4WARD study, showing promising results for mavorixafor in treating chronic neutropenia. The company plans to initiate a Phase II study (4STEPS) in 2027 to evaluate G-CSF reduction. X4 estimates a 15,000-patient U.S. market opportunity, with potential expansion to 30,000 patients. Clinicians highlighted the high disease burden and need for new treatments.

$XFORLow

Virtual Investor Day October 29, 2026 Nasdaq: XFOR

X4 Pharmaceuticals, Inc (XFOR) filed an SEC Form 8-K — Other Events. Virtual Investor Day October 29, 2026 Nasdaq: XFOR Exhibit 99.1 2 This presentation, including any printed or electronic copy of these slides, the talks given by the presenters, the information communicated during any delivery of the presentation and any question-and-answer sessi

X4 Pharmaceuticals to Host Virtual Investor Day on Thursday, October 29, 2026, Featuring Key Opinion Leaders

X4 Pharmaceuticals (XFOR) will host a virtual Investor Day on October 29, 2026, to discuss mavorixafor as a potential treatment for chronic neutropenia. The company will review the Phase 3 4WARD trial and outline a planned Phase 2 trial. Key opinion leaders in hematology will participate in discussions about the drug's potential commercial opportunity.

X4 Pharmaceuticals, Inc (XFOR): Entry into a Material Definitive Agreement

X4 Pharmaceuticals, Inc (XFOR) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. Exhibit 99.1 X4 Pharmaceuticals Secures Up to $150 Million Senior Debt Facility with K2 HealthVentures - Repayment of Existing Loan Facility Completed - - Strengthens Financial Flexibility with Access to Funding for Corporate and Commercial Activities - - Expect Completion of Enr

$XFORMedAI 8/10

X4 Pharmaceuticals Announces Positive Outcome from FDA Type C Meeting

X4 Pharmaceuticals (XFOR) reported a positive FDA Type C meeting outcome, reducing the 4WARD Phase 3 trial sample size from 176 to 126 participants. The FDA agreed the revised size maintains adequate power. The company expects enrollment completion by year-end 2026 and topline data in H1 2028. Mavorixafor targets chronic neutropenia, a rare disease with limited therapy options.

Related tickers