$ZLDPF

Zealand Pharma A/S/ADR

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Zealand Pharma shares fall 12% after obesity drug trial flags side effects

Zealand Pharma's shares dropped 12.5% after a Phase III trial of its obesity drug survodutide showed significant weight loss in type 2 diabetes patients, but 18% discontinued due to gastrointestinal side effects. The trial met its main goals, with patients losing up to 13.1% body weight. The drug is licensed to Boehringer Ingelheim, which is responsible for its development and commercialization.

Zealand Pharma A/S (ZEAL) Survodutide Hits Phase III With Up To 13.1% Weight Loss

Zealand Pharma reported that Boehringer Ingelheim's survodutide achieved co-primary endpoints in its Phase III trial, with participants experiencing up to 13.1% weight loss compared to 3.1% for placebo over 76 weeks. The drug also improved glycemic control in adults with obesity or type 2 diabetes, according to the company.

Zealand Pharma Gets Positive EU Opinion For Zeydovio In Short Bowel Syndrome

Zealand Pharma (ZEAL.CO) announced a positive EU opinion for Zeydovio (glepaglutide) in treating short bowel syndrome, based on Phase 3 trial data. The CHMP recommendation, supported by significant trial results, awaits European Commission approval. The company is also advancing a U.S. trial for potential FDA submission.

ZLDPF sentiment & insider activity

Recent ZLDPF coverage spans financial news, corporate actions and regulation.

What's driving ZLDPF

  • Zealand Pharma's shares dropped 12.5% after a Phase III trial of its obesity drug survodutide showed significant weight loss in type 2 diabetes patients, but 18% discontinued due to gastrointestinal side effects. The trial met its main goals, with patients losing up to 13.1% body weight. The drug is licensed to Boehringer Ingelheim, which is responsible for its development and commercialization.

    investing.com · Oct 1, 2026

  • Zealand Pharma reported that Boehringer Ingelheim's survodutide achieved co-primary endpoints in its Phase III trial, with participants experiencing up to 13.1% weight loss compared to 3.1% for placebo over 76 weeks. The drug also improved glycemic control in adults with obesity or type 2 diabetes, according to the company.

    tradingview.com · Oct 1, 2026

  • Zealand Pharma (ZEAL.CO) announced a positive EU opinion for Zeydovio (glepaglutide) in treating short bowel syndrome, based on Phase 3 trial data. The CHMP recommendation, supported by significant trial results, awaits European Commission approval. The company is also advancing a U.S. trial for potential FDA submission.

    rttnews.com · Sep 18, 2026

  • Royalty Pharma (RPRX) agreed to a $100M deal with Zealand Pharma for rights to a rare blood disorder therapy. RPRX shares are down 1.86% to $60.58, but up 11.16% over 90 days and 70.08% over a year. Analysts debate its valuation, with some calling it 2% overvalued at $59.25, while a DCF model suggests it's heavily discounted at $195.31.

    sahmcapital.com · Aug 22, 2026

  • Jefferies downgraded Zealand Pharma (ZELA) from Buy to Hold and cut its price target to DKK 320 from DKK 505, citing no near-term value catalysts in 2H 2026. It reduced the probability of success for survodutide to 40% from 60% due to tolerability concerns after Phase III data. Shares fell about 2% with no Zealand-specific news.

    investing.com · Jul 14, 2026

AlphAI scores every news story that mentions ZLDPF with an AI model for sentiment and relevance, and aggregates insider trades from Zealand Pharma A/S/ADR's SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $ZLDPF

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HighAI 8/10

Zealand Pharma shares fall 12% after obesity drug trial flags side effects

Zealand Pharma's shares dropped 12.5% after a Phase III trial of its obesity drug survodutide showed significant weight loss in type 2 diabetes patients, but 18% discontinued due to gastrointestinal side effects. The trial met its main goals, with patients losing up to 13.1% body weight. The drug is licensed to Boehringer Ingelheim, which is responsible for its development and commercialization.

MedAI 8/10

Why is Zealand Pharma stock sliding today? By Investing.com

Jefferies downgraded Zealand Pharma (ZELA) from Buy to Hold and cut its price target to DKK 320 from DKK 505, citing no near-term value catalysts in 2H 2026. It reduced the probability of success for survodutide to 40% from 60% due to tolerability concerns after Phase III data. Shares fell about 2% with no Zealand-specific news.

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