Keros Therapeutics Announces the First Patient Dosing in the Phase 2 Clinical Trial Evaluating Rinvatercept in DMD

Oracle (ORCL) and Dell (DELL) are key players in AI infrastructure, with different business models. ORCL has $638B in RPO, expects 34% revenue growth, but faces financial strain. DELL has a $95B AI server backlog, raised FY2027 guidance to $192B revenue, and $25.50 EPS. ORCL trades at 15.21x P/E, DELL at 19.67x. ORCL is down 29.7% YTD, DELL up 347.2%.

Piper Sandler analyst Thomas Champion forecasts Google's external Tensor Processing Unit (TPU) business to generate $104 billion in revenue by 2028, up from $8 billion in 2026. The firm raised its Alphabet price target to $400 from $395, citing potential growth in AI chip demand. Alphabet shares fell 0.7% in premarket trading.

MediciNova Inc (MNOV) shares dropped 14.7% premarket after its Phase 2 trial for MN-001 in nonalcoholic fatty liver disease and hypertriglyceridemia missed primary endpoints at 24 weeks. While MN-001 showed early triglyceride reduction, the effect wasn't sustained. HDL cholesterol and particle concentration improvements were statistically significant. The company plans to assess next steps for development.

IREN Limited (IREN) fell 3% premarket after Jones Trading initiated coverage with a Hold rating, citing growth challenges despite strong AI demand. Analyst Kevin Dede noted IREN's vast customer base and Microsoft (MSFT) as its sole investment-grade customer. IREN recently secured a $5.5B deal with Nvidia (NVDA). Dede highlighted concerns over retail ownership and executive compensation but acknowledged industry demand.

Dell Technologies reported a $95 billion AI server backlog after a record quarter, with $60.9 billion in new orders. Its Infrastructure Solutions Group revenue rose 89% YoY to $31.8 billion. Goldman Sachs projects the AI server market could reach $1.24 trillion by 2030. Dell's stock has surged 347% in 2026, with some investors predicting it could nearly triple by 2030, though risks include order delays and margin pressures.

NVIDIA launched the Open Agent Safety Platform to secure autonomous AI systems. It combines OpenShell, an open-source runtime for policy enforcement, and Sentry, a hardware-based watchdog. Over 100 organizations, including Microsoft and Salesforce, are using the platform. NVIDIA aims to address AI agents bypassing controls and provide hardware-level monitoring. The platform is available through NVIDIA's developer resources and GitHub.