Two cholesterol measures improved significantly, but the trial missed its primary endpoints.
MediciNova (MNOV) reported Phase 2 trial results for MN-001 in treating nonalcoholic fatty liver disease and hypertriglyceridemia. While primary endpoints were not met, significant improvements in HDL-C and HDL-P were observed. MN-001 was well-tolerated. The company plans further analysis and will assess next steps. Additionally, MediciNova is on track to report topline results for its Phase 2b/3 trial of MN-166 in ALS by year-end.