Medicenna Therapeutics Corp. (MDNA) Sets Oral Presentation of MDNA11 Topline Data at SITC 2026

Amazon CEO Andy Jassy stated that AWS computing capacity for 2027 is largely booked, with a 'good chunk' of 2028 also sold. AWS revenue grew 37% to $42.2 billion in Q2 2026. Amazon plans $220 billion in capex for 2026, with free cash flow at a $7.6 billion outflow. Analysts have a Strong Buy consensus with a $331.46 average price target. Q3 earnings are expected on October 29, 2026.

Apple (AAPL) launched the iPhone Duo, its first foldable smartphone, priced at $1,999. The device features a 7.6-inch interior and 5.4-inch exterior display. IDC forecasts Apple to capture 31% of global foldable smartphone shipments and 44% of market revenue by 2026, rising to 40% and 52% by 2027. Pre-orders began October 16, with some deliveries delayed until 2027, indicating high demand or supply constraints.

Oracle plans to invest $1 billion to boost partner growth and AI-driven modernization. The funds will support building new offerings, pursuing business opportunities, and enhancing customer success, according to the company.

Exploratory analyses of the phase 3 CROWN trial presented at the 2026 ESMO Congress found that baseline and on-treatment ctDNA features, including TP53 mutations, were linked to early progression or prolonged PFS with first-line lorlatinib in ALK-positive NSCLC. Early progressors had more altered genes and TP53 mutations. Undetectable tumor fraction at baseline and its clearance by week 4 were associated with longer PFS.

Johnson & Johnson reported a phase 3 study showing apalutamide plus hormone therapy before and after surgery reduced recurrence-related events or death in high-risk prostate cancer. The study involved 408 patients, with a 62% reduction in hazard for the treatment group. The company noted the regimen is not yet approved for this use.

Boeing's 777 Freighter production was halted for nearly two months due to a dispute with supplier Vaero, according to Reuters. The disruption also affected 767 output, including freighters and KC-46 tankers. Boeing alleged daily costs of up to $6.5m. Emirates ordered five additional 777Fs in October 2024. Boeing declined to comment, and Vaero and FedEx did not respond to requests.