$ANRO

Alto Neuroscience, Inc.

Alto Neuroscience is a clinical-stage biopharmaceutical company developing treatments for psychiatric and neurological conditions. Its precision psychiatry platform analyzes neurocognitive assessments, EEG, wearable-device data and genetic and genomic samples to identify biomarkers that may help select patients likely to respond to treatment. Alto has seven clinical-stage assets for conditions including major depressive disorder, bipolar depression, treatment-resistant depression, schizophrenia and Parkinson’s disease. Its candidates include ALTO-207, a fixed-dose combination being developed for treatment-resistant depression; ALTO-300, an investigational oral antidepressant being studied for biomarker-selected patients with major depressive disorder; and ALTO-101, a transdermal candidate for cognitive impairment associated with schizophrenia. Alto’s stated activities focus on developing its product candidates through clinical trials, using biomarker insights to guide drug development and patient selection. Its platform also includes software tools for biomarker data collection, including Spectra, TechCheck and Altoscope.

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Alto Neuroscience earnings up next as investors eye 2027 catalysts

Alto Neuroscience Inc. reports Q3 results Wednesday, with analysts expecting a loss of $0.82 per share. The company, which has no revenue, has seen EPS estimates decline 2.68% over 60 days. Despite losses, analysts rate it a Strong Buy with a $38.67 price target, implying 39% upside. Investors focus on cash runway and trial progress, particularly ALTO-207 for treatment-resistant depression, with key readouts expected in 2027.

ANRO sentiment & insider activity

Recent ANRO coverage spans financial news, earnings and corporate actions.

What's driving ANRO

  • Alto Neuroscience Inc. reports Q3 results Wednesday, with analysts expecting a loss of $0.82 per share. The company, which has no revenue, has seen EPS estimates decline 2.68% over 60 days. Despite losses, analysts rate it a Strong Buy with a $38.67 price target, implying 39% upside. Investors focus on cash runway and trial progress, particularly ALTO-207 for treatment-resistant depression, with key readouts expected in 2027.

    investing.com · Nov 10, 2026

  • HC Wainwright & Co. reiterated a Buy rating and $60 price target for Alto Neuroscience, implying a 173.5% upside from the Oct 16 close of $21.94. The firm cited strong clinical evidence and significant market potential for the company's psychiatric treatments.

    tradingview.com · Oct 19, 2026

  • Alto Neuroscience's President and CFO, Nicholas Conrad Smith, sold shares worth $3.57M under a 10b5-1 plan, at average prices of $26.58, $25.78, and $26.87. He now directly owns 24,060 shares, according to an SEC filing.

    tradingview.com · Oct 2, 2026

  • Insider sale may signal reduced confidence, creating slight downside pressure.

    SEC EDGAR · Oct 2, 2026

  • Executive promotion with sizable retention payout may affect investor perception of leadership stability and cash usage.

    SEC EDGAR 8-K · Aug 27, 2026

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News on $ANRO

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Alto Neuroscience earnings up next as investors eye 2027 catalysts

Alto Neuroscience Inc. reports Q3 results Wednesday, with analysts expecting a loss of $0.82 per share. The company, which has no revenue, has seen EPS estimates decline 2.68% over 60 days. Despite losses, analysts rate it a Strong Buy with a $38.67 price target, implying 39% upside. Investors focus on cash runway and trial progress, particularly ALTO-207 for treatment-resistant depression, with key readouts expected in 2027.

Alto Neuroscience, Inc. (ANRO): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Alto Neuroscience, Inc. (ANRO) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. On August 26, 2026 (the “ Effective Date” ), the Board of Directors (the “ Board ”) of Alto Neuroscience, Inc. (the “ Compa

Alto Neuroscience Reports Second Quarter 2026 Financial Results and Recent

Alto Neuroscience, Inc. (ANRO) filed an SEC Form 8-K — Results of Operations and Financial Condition. Exhibit 99.1 Alto Neuroscience Reports Second Quarter 2026 Financial Results and Recent Business Highlights – ALTO-207 development expanded: an additional Phase 3 trial evaluating ALTO-207 as monotherapy in treatment-resistant depression (TRD) is now planned, alongside the ongoin

Biotech Stocks Hit 52-Week Highs - TOI, IKT, ANRO, ELV, PRVA

Biotech and healthcare stocks hit 52-week highs on July 14, 2026. The Oncology Institute (TOI) reached $6.66 after repaying an $86 million senior convertible note and projecting 2026 revenue of $630 million to $650 million. Inhibikase (IKT) rose above $2.36 after a $50 million ATM sale. Alto Neuroscience (ANRO) hit $28.85 after a $100 million direct offering. Elevance (ELV) touched $434.38, guiding 2026 adjusted diluted EPS of at least $26.75. Privia (PRVA) hit $28.30, estimating 2026 GAAP reven

Alto Neuroscience, Inc. (ANRO): Entry into a Material Definitive Agreement

Alto Neuroscience, Inc. (ANRO) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. EX-1.1 2 tm2620328d1_ex1-1.htm EXHIBIT 1.1 Exhibit 1.1 ALTO NEUROSCIENCE, INC. (a Delaware corporation) 3,776,436 Shares of Common Stock UNDERWRITING AGREEMENT Dated: July 13, 2026 ALTO NEUROSCIENCE, INC. (a Delaware corporation) 3,776,436 Shares of Common Stock UNDERWRITING AGRE

Alto Neuroscience, Inc. (ANRO): Results of Operations and Financial Condition

Alto Neuroscience, Inc. (ANRO) filed an SEC Form 8-K — Results of Operations and Financial Condition. false 0001999480 0001999480 2026-07-13 2026-07-13 iso4217:USD xbrli:shares iso4217:USD xbrli:shares UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Repor

Alto Neuroscience reports Q1 2026 net loss of $26.2M, cash of $264.2M after $120M PIPE

Alto Neuroscience reported a net loss of $26.2 million for Q1 2026, an increase from $15.2 million in Q1 2025, but ended the quarter with $264.2 million in cash following a March PIPE financing. The company expects this funding to support operations through 2029, including a potential NDA submission for ALTO-207. Key business highlights include the initiation of a Phase 2b trial for ALTO-207, advancements with ALTO-101, and ongoing Phase 2b trials for ALTO-300 and ALTO-100 with projected topline readouts in 2027.

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