$CRDF

Cardiff Oncology, Inc.

Cardiff Oncology is a clinical-stage biotechnology company developing cancer therapies based on PLK1 inhibition. Its programs focus on onvansertib, an oral PLK1 inhibitor, in combination with standard-of-care treatments, with clinical studies in RAS-mutated metastatic colorectal cancer and investigator-initiated trials in pancreatic cancer, small cell lung cancer, triple-negative breast cancer and chronic myelomonocytic leukemia. The company also uses tumor genomics and biomarker assays to guide patient selection and assess treatment response. Cardiff Oncology conducts its business in one segment and relies on third-party manufacturers and distributors to supply and distribute onvansertib for clinical studies and nonclinical development. Its clinical programs include a randomized Phase 2 trial in first-line RAS-mutated metastatic colorectal cancer and studies of onvansertib alone or in combination with other therapies. Cardiff Oncology is headquartered in San Diego, California, where it also has a laboratory.

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Cardiff Oncology, Inc. (CRDF): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Cardiff Oncology, Inc. (CRDF) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. Exhibit 99.1 Cardiff Oncology Appoints Leila Alland, MD, as Interim Chief Medical Officer Seasoned oncology executive brings extensive clinical development expertise and a track record of advancing innovative cancer therapies SAN DIEGO, Calif., October 27, 2026 — Cardiff Oncology

Cardiff Oncology names Leila Alland interim chief medical officer

Cardiff Oncology (CRDF) appointed Leila Alland, MD, as interim Chief Medical Officer. The company's Phase 2 trial for onvansertib in metastatic colorectal cancer shows median progression-free survival not yet reached. A Phase 3 study is planned for Q1 2027. Alland has extensive experience in oncology drug development.

Cardiff Oncology, Inc. (CRDF): Submission of Matters to a Vote of Security Holders

Cardiff Oncology, Inc. (CRDF) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. Item 5.07 Submission of Matters to a Vote of Security Holders On October 22, 2026, Cardiff Oncology, Inc. (the “Company”) held its Special Meeting of Stockholders (the “Special Meeting”). A total of 48,084,246 shares of common stock, constituting a quorum, were represented in per

CRDF sentiment & insider activity

Over the past 7 days, AlphAI's AI scored 4 news stories mentioning CRDF (Cardiff Oncology, Inc.). Coverage has skewed bearish: 0 bullish, 3 neutral, and 1 bearish.

Recent CRDF coverage spans corporate actions, financial news and insider activity.

What's driving CRDF

AlphAI scores every news story that mentions CRDF with an AI model for sentiment and relevance, and aggregates insider trades from Cardiff Oncology, Inc.'s SEC EDGAR Form 4 filings. Figures refresh continuously.

News on $CRDF

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$CRDFLow

Cardiff Oncology, Inc. (CRDF): Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Cardiff Oncology, Inc. (CRDF) filed an SEC Form 8-K — Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers. Exhibit 99.1 Cardiff Oncology Appoints Leila Alland, MD, as Interim Chief Medical Officer Seasoned oncology executive brings extensive clinical development expertise and a track record of advancing innovative cancer therapies SAN DIEGO, Calif., October 27, 2026 — Cardiff Oncology

$CRDFLow

Cardiff Oncology, Inc. (CRDF): Submission of Matters to a Vote of Security Holders

Cardiff Oncology, Inc. (CRDF) filed an SEC Form 8-K — Submission of Matters to a Vote of Security Holders. Item 5.07 Submission of Matters to a Vote of Security Holders On October 22, 2026, Cardiff Oncology, Inc. (the “Company”) held its Special Meeting of Stockholders (the “Special Meeting”). A total of 48,084,246 shares of common stock, constituting a quorum, were represented in per

$CRDFMedAI 8/10

FDA grants orphan drug status to Cardiff’s onvansertib for CMML

Cardiff Oncology (CRDF) received FDA Orphan Drug Designation for onvansertib to treat chronic myelomonocytic leukemia (CMML). The drug showed preliminary efficacy in a Phase 1 trial, with benefits including platelet response and stable disease. Orphan Drug Designation offers tax credits, fee exemptions, and market exclusivity. CRDF is developing onvansertib for other cancers as well.

$PDSBMed

Biotech Stocks Gain Ground: PDS Biotech, Clene, Indaptus Lead Movers

PDS Biotech (PDSB) announced a $22.55M PIPE financing for late-stage cancer drug development, shares up 50.64%. Avaí Bio (AVAI) completed cell bank testing, shares up 14.29%. Clene (CLNN) priced a $4M offering, shares up 25.25%. NurExone (NRX.V) partnered with NanoPass, shares up 8.06%. Cardiff Oncology (CRDF) settled a licensing dispute, shares up 4.58%. Indaptus (INDP) shares surged 16.88% without specific news.

$CRDFMed

Cardiff Oncology, Inc. (CRDF): Entry into a Material Definitive Agreement

Cardiff Oncology, Inc. (CRDF) filed an SEC Form 8-K — Entry into a Material Definitive Agreement. Exhibit 99.1 Cardiff Oncology and Nerviano Medical Sciences Amend their 2017 Exclusive License Agreement Under the terms of the Amendment, all disputed issues are resolved SAN DIEGO and NERVIANO, Italy, September 14, 2026 — Cardiff Oncology, Inc. (NASDAQ: CRDF) (“Cardiff”) and Ne

$CRDFMed

Cardiff Oncology Reports Second Quarter 2026 Results and Provides Business Update

Cardiff Oncology, Inc. (CRDF) filed an SEC Form 8-K — Results of Operations and Financial Condition. Cardiff Oncology Reports Second Quarter 2026 Results and Provides Business Update Positive Phase 2 CRDF-004 data presented in an oral session at ASCO support advancement of 30 mg onvansertib plus FOLFIRI/bevacizumab into planned registrational program for first-line RAS-mutated m

$ADILLow

Thursday’s insider activity: Major sells dominate trading By Investing.com

Investing.com reported U.S. insider trading for July 16, 2026. Major buys included Boundless Bio (63,969 shares, about $155.6k), ADIAL Pharmaceuticals (3,233 shares, $8,690), FIS (1,386 shares, $57.4k) and Cardiff Oncology (34,364 shares plus warrants). Major sells included Celcuity (3.1M shares, about $317.8M), Arista Networks (300k shares, about $54.2M), Butterfly Network (4.0M shares, about $29.4M), CoreWeave (307,692 shares, about $24.8M) and Venture Global (555,556 shares, about $14.3M).

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